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p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis

by: Xiaohua Su, Deepavali Chakravarti, Elsa R. Flores
Nat Rev Cancer, Vol. 13, No. 2. (24 February 2013), pp. 136-143, doi:10.1038/nrc3446  Key: citeulike:11931518

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Abstract

The role of p63 in cancer has been an area of intense debate and controversy. Is TP63 (which encodes p63) a tumour suppressor gene or an oncogene? This debate is partly due to the complexity of the gene. There are several p63 isoforms 


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