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Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma

by: Alla Arzumanyan, Helena M. G. P. V. Reis, Mark A. Feitelson
Nat Rev Cancer, Vol. 13, No. 2. (24 February 2013), pp. 123-135, doi:10.1038/nrc3449  Key: citeulike:11931519

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Abstract

Hepatocellular carcinoma (HCC) is a highly lethal cancer, with increasing worldwide incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C virus (HCV) infections. There are few effective treatments partly because the cell- and molecular-based mechanisms that contribute to the pathogenesis


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