Cervical-vaginal and intraanal human papillomavirus infection of young girls with external genital warts Export

@article{Gutman1994, abstract = {To expand information regarding the epidemiology of genital human papillomavirus (HPV) infection in young girls, girls with external genital warts were examined for the prevalence of cervical-vaginal or intraanal HPV infection. Cervical-vaginal wash specimens and biopsies of external lesions were examined for HPV genotypes 1, 2, 4, 6, 11, and 16 using Southern transfer hybridization with restriction endonuclease fragment length analysis. Exfoliated cells from cervical-vaginal and intraanal canals were processed for cytologic study. Of 18 girls, 8 (44\%) had cytologic or genomic evidence (or both) of cervical-vaginal or intraanal HPV infection. Five had cervical-vaginal wash specimens that were positive for HPV genome and showed mild dysplasia. As is true for adults, young girls with external anal-genital warts are also frequently infected with HPV at internal mucosal sites. Determining the immediate and long-term prognosis of infected children and those with intraepithelial neoplasia will require appropriate prospective studies.}, author = {Gutman, L. T. and St Claire, K. K. and Everett, V. D. and Ingram, D. L. and Soper, J. and Johnston, W. W. and Mulvaney, G. G. and Phelps, W. C.}, citeulike-article-id = {1130029}, citeulike-linkout-0 = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8035020}, journal = {J Infect Dis}, keywords = {abuse, acuminatacomplications, anus, atlas, blotting, cervical, cervix, child, condylomata, diseases, diseasescomplicationsepidemiology, dna, dysplasiacomplicationsepidemiology, female, femalecomplications, genital, genome, humanclassificationgeneticsisolation, humans, infant, infectionscomplicationsepidemiology, papillomavirus, papovaviridae, preschool, prevalence, purification, sexual, smears, southern, tumor, uterine, uteripathologyvirology, vaginal, vaginapathologyvirology, viral, viralanalysis, virus}, month = {Aug}, number = {2}, pages = {339--44}, posted-at = {2007-02-28 15:55:51}, priority = {2}, title = {Cervical-vaginal and intraanal human papillomavirus infection of young girls with external genital warts}, url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8035020}, volume = {170}, year = {1994} }

TY - JOUR ID - Gutman1994 L3 - citeulike-article-id:1130029 N2 - To expand information regarding the epidemiology of genital human papillomavirus (HPV) infection in young girls, girls with external genital warts were examined for the prevalence of cervical-vaginal or intraanal HPV infection. Cervical-vaginal wash specimens and biopsies of external lesions were examined for HPV genotypes 1, 2, 4, 6, 11, and 16 using Southern transfer hybridization with restriction endonuclease fragment length analysis. Exfoliated cells from cervical-vaginal and intraanal canals were processed for cytologic study. Of 18 girls, 8 (44%) had cytologic or genomic evidence (or both) of cervical-vaginal or intraanal HPV infection. Five had cervical-vaginal wash specimens that were positive for HPV genome and showed mild dysplasia. As is true for adults, young girls with external anal-genital warts are also frequently infected with HPV at internal mucosal sites. Determining the immediate and long-term prognosis of infected children and those with intraepithelial neoplasia will require appropriate prospective studies. IS - 2 JF - J Infect Dis EP - 44 TI - Cervical-vaginal and intraanal human papillomavirus infection of young girls with external genital warts VL - 170 SP - 339 KW - abuse KW - acuminatacomplications KW - anus KW - atlas KW - blotting KW - cervical KW - cervix KW - child KW - condylomata KW - diseases KW - diseasescomplicationsepidemiology KW - dna KW - dysplasiacomplicationsepidemiology KW - female KW - femalecomplications KW - genital KW - genome KW - humanclassificationgeneticsisolation KW - humans KW - infant KW - infectionscomplicationsepidemiology KW - papillomavirus KW - papovaviridae KW - preschool KW - prevalence KW - purification KW - sexual KW - smears KW - southern KW - tumor KW - uterine KW - uteripathologyvirology KW - vaginal KW - vaginapathologyvirology KW - viral KW - viralanalysis KW - virus AU - Gutman, LT AU - St Claire, KK AU - Everett, VD AU - Ingram, DL AU - Soper, J AU - Johnston, WW AU - Mulvaney, GG AU - Phelps, WC PY - 1994/Aug// UR - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8035020 ER -