Evolution of genes and genomes on the Drosophila phylogeny. Export

@article{citeulike:1880603, abstract = {Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.}, author = {{Drosophila 12 Genomes Consortium} and Clark, Andrew G. and Eisen, Michael B. and Smith, Douglas R. and Bergman, Casey M. and Oliver, Brian and Markow, Therese A. and Kaufman, Thomas C. and Kellis, Manolis and Gelbart, William and Iyer, Venky N. and Pollard, Daniel A. and Sackton, Timothy B. and Larracuente, Amanda M. and Singh, Nadia D. and Abad, Jose P. and Abt, Dawn N. and Adryan, Boris and Aguade, Montserrat and Akashi, Hiroshi and Anderson, Wyatt W. and Aquadro, Charles F. and Ardell, David H. and Arguello, Roman and Artieri, Carlo G. and Barbash, Daniel A. and Barker, Daniel and Barsanti, Paolo and Batterham, Phil and Batzoglou, Serafim and Begun, Dave and Bhutkar, Arjun and Blanco, Enrico and Bosak, Stephanie A. and Bradley, Robert K. and Brand, Adrianne D. and Brent, Michael R. and Brooks, Angela N. and Brown, Randall H. and Butlin, Roger K. and Caggese, Corrado and Calvi, Brian R. and Bernardo de Carvalho, A. and Caspi, Anat and Castrezana, Sergio and Celniker, Susan E. and Chang, Jean L. and Chapple, Charles and Chatterji, Sourav and Chinwalla, Asif and Civetta, Alberto and Clifton, Sandra W. and Comeron, Josep M. and Costello, James C. and Coyne, Jerry A. and Daub, Jennifer and David, Robert G. and Delcher, Arthur L. and Delehaunty, Kim and Do, Chuong B. and Ebling, Heather and Edwards, Kevin and Eickbush, Thomas and Evans, Jay D. and Filipski, Alan and Findeiss, Sven and Freyhult, Eva and Fulton, Lucinda and Fulton, Robert and Garcia, Ana C. and Gardiner, Anastasia and Garfield, David A. and Garvin, Barry E. and Gibson, Greg and Gilbert, Don and Gnerre, Sante and Godfrey, Jennifer and Good, Robert and Gotea, Valer and Gravely, Brenton and Greenberg, Anthony J. and Griffiths-Jones, Sam and Gross, Samuel and Guigo, Roderic and Gustafson, Erik A. and Haerty, Wilfried and Hahn, Matthew W. and Halligan, Daniel L. and Halpern, Aaron L. and Halter, Gillian M. and Han, Mira V. and Heger, Andreas and Hillier, LaDeana and Hinrichs, Angie S. and Holmes, Ian and Hoskins, Roger A. and Hubisz, Melissa J. and Hultmark, Dan and Huntley, Melanie A. and Jaffe, David B. and Jagadeeshan, Santosh and Jeck, William R. and Johnson, Justin and Jones, Corbin D. and Jordan, William C. and Karpen, Gary H. and Kataoka, Eiko and Keightley, Peter D. and Kheradpour, Pouya and Kirkness, Ewen F. and Koerich, Leonardo B. and Kristiansen, Karsten and Kudrna, Dave and Kulathinal, Rob J. and Kumar, Sudhir and Kwok, Roberta and Lander, Eric and Langley, Charles H. and Lapoint, Richard and Lazzaro, Brian P. and Lee, So-Jeong J. and Levesque, Lisa and Li, Ruiqiang and Lin, Chiao-Feng F. and Lin, Michael F. and Lindblad-Toh, Kerstin and Llopart, Ana and Long, Manyuan and Low, Lloyd and Lozovsky, Elena and Lu, Jian and Luo, Meizhong and Machado, Carlos A. and Makalowski, Wojciech and Marzo, Mar and Matsuda, Muneo and Matzkin, Luciano and McAllister, Bryant and McBride, Carolyn S. and McKernan, Brendan and McKernan, Kevin and Mendez-Lago, Maria and Minx, Patrick and Mollenhauer, Michael U. and Montooth, Kristi and Mount, Stephen M. and Mu, Xu and Myers, Eugene and Negre, Barbara and Newfeld, Stuart and Nielsen, Rasmus and Noor, Mohamed A. and O'Grady, Patrick and Pachter, Lior and Papaceit, Montserrat and Parisi, Matthew J. and Parisi, Michael and Parts, Leopold and Pedersen, Jakob S. and Pesole, Graziano and Phillippy, Adam M. and Ponting, Chris P. and Pop, Mihai and Porcelli, Damiano and Powell, Jeffrey R. and Prohaska, Sonja and Pruitt, Kim and Puig, Marta and Quesneville, Hadi and Ram, Kristipati Ravi R. and Rand, David and Rasmussen, Matthew D. and Reed, Laura K. and Reenan, Robert and Reily, Amy and Remington, Karin A. and Rieger, Tania T. and Ritchie, Michael G. and Robin, Charles and Rogers, Yu-Hui H. and Rohde, Claudia and Rozas, Julio and Rubenfield, Marc J. and Ruiz, Alfredo and Russo, Susan and Salzberg, Steven L. and Sanchez-Gracia, Alejandro and Saranga, David J. and Sato, Hajime and Schaeffer, Stephen W. and Schatz, Michael C. and Schlenke, Todd and Schwartz, Russell and Segarra, Carmen and Singh, Rama S. and Sirot, Laura and Sirota, Marina and Sisneros, Nicholas B. and Smith, Chris D. and Smith, Temple F. and Spieth, John and Stage, Deborah E. and Stark, Alexander and Stephan, Wolfgang and Strausberg, Robert L. and Strempel, Sebastian and Sturgill, David and Sutton, Granger and Sutton, Granger G. and Tao, Wei and Teichmann, Sarah and Tobari, Yoshiko N. and Tomimura, Yoshihiko and Tsolas, Jason M. and Valente, Vera L. and Venter, Eli and Venter, J. Craig and Vicario, Saverio and Vieira, Filipe G. and Vilella, Albert J. and Villasante, Alfredo and Walenz, Brian and Wang, Jun and Wasserman, Marvin and Watts, Thomas and Wilson, Derek and Wilson, Richard K. and Wing, Rod A. and Wolfner, Mariana F. and Wong, Alex and Wong, Gane Ka-Shu K. and Wu, Chung-I I. and Wu, Gabriel and Yamamoto, Daisuke and Yang, Hsiao-Pei P. and Yang, Shiaw-Pyng P. and Yorke, James A. and Yoshida, Kiyohito and Zdobnov, Evgeny and Zhang, Peili and Zhang, Yu and Zimin, Aleksey V. and Baldwin, Jennifer and Abdouelleil, Amr and Abdulkadir, Jamal and Abebe, Adal and Abera, Brikti and Abreu, Justin and Acer, St Christophe C. and Aftuck, Lynne and Alexander, Allen and An, Peter and Anderson, Erica and Anderson, Scott and Arachi, Harindra and Azer, Marc and Bachantsang, Pasang and Barry, Andrew and Bayul, Tashi and Berlin, Aaron and Bessette, Daniel and Bloom, Toby and Blye, Jason and Boguslavskiy, Leonid and Bonnet, Claude and Boukhgalter, Boris and Bourzgui, Imane and Brown, Adam and Cahill, Patrick and Channer, Sheridon and Cheshatsang, Yama and Chuda, Lisa and Citroen, Mieke and Collymore, Alville and Cooke, Patrick and Costello, Maura and D'Aco, Katie and Daza, Riza and De Haan, Georgius and DeGray, Stuart and DeMaso, Christina and Dhargay, Norbu and Dooley, Kimberly and Dooley, Erin and Doricent, Missole and Dorje, Passang and Dorjee, Kunsang and Dupes, Alan and Elong, Richard and Falk, Jill and Farina, Abderrahim and Faro, Susan and Ferguson, Diallo and Fisher, Sheila and Foley, Chelsea D. and Franke, Alicia and Friedrich, Dennis and Gadbois, Loryn and Gearin, Gary and Gearin, Christina R. and Giannoukos, Georgia and Goode, Tina and Graham, Joseph and Grandbois, Edward and Grewal, Sharleen and Gyaltsen, Kunsang and Hafez, Nabil and Hagos, Birhane and Hall, Jennifer and Henson, Charlotte and Hollinger, Andrew and Honan, Tracey and Huard, Monika D. and Hughes, Leanne and Hurhula, Brian and Husby, M. Erii and Kamat, Asha and Kanga, Ben and Kashin, Seva and Khazanovich, Dmitry and Kisner, Peter and Lance, Krista and Lara, Marcia and Lee, William and Lennon, Niall and Letendre, Frances and LeVine, Rosie and Lipovsky, Alex and Liu, Xiaohong and Liu, Jinlei and Liu, Shangtao and Lokyitsang, Tashi and Lokyitsang, Yeshi and Lubonja, Rakela and Lui, Annie and MacDonald, Pen and Magnisalis, Vasilia and Maru, Kebede and Matthews, Charles and McCusker, William and McDonough, Susan and Mehta, Teena and Meldrim, James and Meneus, Louis and Mihai, Oana and Mihalev, Atanas and Mihova, Tanya and Mittelman, Rachel and Mlenga, Valentine and Montmayeur, Anna and Mulrain, Leonidas and Navidi, Adam and Naylor, Jerome and Negash, Tamrat and Nguyen, Thu and Nguyen, Nga and Nicol, Robert and Norbu, Choe and Norbu, Nyima and Novod, Nathaniel and O'Neill, Barry and Osman, Sahal and Markiewicz, Eva and Oyono, Otero L. and Patti, Christopher and Phunkhang, Pema and Pierre, Fritz and Priest, Margaret and Raghuraman, Sujaa and Rege, Filip and Reyes, Rebecca and Rise, Cecil and Rogov, Peter and Ross, Keenan and Ryan, Elizabeth and Settipalli, Sampath and Shea, Terry and Sherpa, Ngawang and Shi, Lu and Shih, Diana and Sparrow, Todd and Spaulding, Jessica and Stalker, John and Stange-Thomann, Nicole and Stavropoulos, Sharon and Stone, Catherine and Strader, Christopher and Tesfaye, Senait and Thomson, Talene and Thoulutsang, Yama and Thoulutsang, Dawa and Topham, Kerri and Topping, Ira and Tsamla, Tsamla and Vassiliev, Helen and Vo, Andy and Wangchuk, Tsering and Wangdi, Tsering and Weiand, Michael and Wilkinson, Jane and Wilson, Adam and Yadav, Shailendra and Young, Geneva and Yu, Qing and Zembek, Lisa and Zhong, Danni and Zimmer, Andrew and Zwirko, Zac and Jaffe, David B. and Alvarez, Pablo and Brockman, Will and Butler, Jonathan and Chin, CheeWhye and Gnerre, Sante and Grabherr, Manfred and Kleber, Michael and Mauceli, Evan and MacCallum, Iain}, citeulike-article-id = {1880603}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nature06341}, citeulike-linkout-1 = {http://adsabs.harvard.edu/cgi-bin/nph-bib_query?bibcode=2007Natur.450..203C}, citeulike-linkout-2 = {http://dx.doi.org/10.1038/nature06341}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/17994087}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=17994087}, day = {8}, doi = {10.1038/nature06341}, issn = {1476-4687}, journal = {Nature}, keywords = {drosophila, evolution, gene}, month = {November}, number = {7167}, pages = {203--218}, posted-at = {2008-10-28 15:01:33}, priority = {2}, publisher = {Nature Publishing Group}, title = {Evolution of genes and genomes on the Drosophila phylogeny.}, url = {http://dx.doi.org/10.1038/nature06341}, volume = {450}, year = {2007} }

TY - JOUR ID - citeulike:1880603 L3 - citeulike-article-id:1880603 N2 - Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species. IS - 7167 JF - Nature SN - 1476-4687 EP - 218 TI - Evolution of genes and genomes on the Drosophila phylogeny. PB - Nature Publishing Group VL - 450 SP - 203 KW - drosophila KW - evolution KW - gene AU - Clark, Andrew AU - Eisen, Michael AU - Smith, Douglas AU - Bergman, Casey AU - Oliver, Brian AU - Markow, Therese AU - Kaufman, Thomas AU - Kellis, Manolis AU - Gelbart, William AU - Iyer, Venky AU - Pollard, Daniel AU - Sackton, Timothy AU - Larracuente, Amanda AU - Singh, Nadia AU - Abad, Jose AU - Abt, Dawn AU - Adryan, Boris AU - Aguade, Montserrat AU - Akashi, Hiroshi AU - Anderson, Wyatt AU - Aquadro, Charles AU - Ardell, David AU - Arguello, Roman AU - Artieri, Carlo AU - Barbash, Daniel AU - Barker, Daniel AU - Barsanti, Paolo AU - Batterham, Phil AU - Batzoglou, Serafim AU - Begun, Dave AU - Bhutkar, Arjun AU - Blanco, Enrico AU - Bosak, Stephanie AU - Bradley, Robert AU - Brand, Adrianne AU - Brent, Michael AU - Brooks, Angela AU - Brown, Randall AU - Butlin, Roger AU - Caggese, Corrado AU - Calvi, Brian AU - Bernardo de Carvalho, A AU - Caspi, Anat AU - Castrezana, Sergio AU - Celniker, Susan AU - Chang, Jean AU - Chapple, Charles AU - Chatterji, Sourav AU - Chinwalla, Asif AU - Civetta, Alberto AU - Clifton, Sandra AU - Comeron, Josep AU - Costello, James AU - Coyne, Jerry AU - Daub, Jennifer AU - David, Robert AU - Delcher, Arthur AU - Delehaunty, Kim AU - Do, Chuong AU - Ebling, Heather AU - Edwards, Kevin AU - Eickbush, Thomas AU - Evans, Jay AU - Filipski, Alan AU - Findeiss, Sven AU - Freyhult, Eva AU - Fulton, Lucinda AU - Fulton, Robert AU - Garcia, Ana AU - Gardiner, Anastasia AU - Garfield, David AU - Garvin, Barry AU - Gibson, Greg AU - Gilbert, Don AU - Gnerre, Sante AU - Godfrey, Jennifer AU - Good, Robert AU - Gotea, Valer AU - Gravely, Brenton AU - Greenberg, Anthony AU - Griffiths-Jones, Sam AU - Gross, Samuel AU - Guigo, Roderic AU - Gustafson, Erik AU - Haerty, Wilfried AU - Hahn, Matthew AU - Halligan, Daniel AU - Halpern, Aaron AU - Halter, Gillian AU - Han, Mira AU - Heger, Andreas AU - Hillier, LaDeana AU - Hinrichs, Angie AU - Holmes, Ian AU - Hoskins, Roger AU - Hubisz, Melissa AU - Hultmark, Dan AU - Huntley, Melanie AU - Jaffe, David AU - Jagadeeshan, Santosh AU - Jeck, William AU - Johnson, Justin AU - Jones, Corbin AU - Jordan, William AU - Karpen, Gary AU - Kataoka, Eiko AU - Keightley, Peter AU - Kheradpour, Pouya AU - Kirkness, Ewen AU - Koerich, Leonardo AU - Kristiansen, Karsten AU - Kudrna, Dave AU - Kulathinal, Rob AU - Kumar, Sudhir AU - Kwok, Roberta AU - Lander, Eric AU - Langley, Charles AU - Lapoint, Richard AU - Lazzaro, Brian AU - Lee, So-Jeong AU - Levesque, Lisa AU - Li, Ruiqiang AU - Lin, Chiao-Feng AU - Lin, Michael AU - Lindblad-Toh, Kerstin AU - Llopart, Ana AU - Long, Manyuan AU - Low, Lloyd AU - Lozovsky, Elena AU - Lu, Jian AU - Luo, Meizhong AU - Machado, Carlos AU - Makalowski, Wojciech AU - Marzo, Mar AU - Matsuda, Muneo AU - Matzkin, Luciano AU - McAllister, Bryant AU - McBride, Carolyn AU - McKernan, Brendan AU - McKernan, Kevin AU - Mendez-Lago, Maria AU - Minx, Patrick AU - Mollenhauer, Michael AU - Montooth, Kristi AU - Mount, Stephen AU - Mu, Xu AU - Myers, Eugene AU - Negre, Barbara AU - Newfeld, Stuart AU - Nielsen, Rasmus AU - Noor, Mohamed AU - O'Grady, Patrick AU - Pachter, Lior AU - Papaceit, Montserrat AU - Parisi, Matthew AU - Parisi, Michael AU - Parts, Leopold AU - Pedersen, Jakob AU - Pesole, Graziano AU - Phillippy, Adam AU - Ponting, Chris AU - Pop, Mihai AU - Porcelli, Damiano AU - Powell, Jeffrey AU - Prohaska, Sonja AU - Pruitt, Kim AU - Puig, Marta AU - Quesneville, Hadi AU - Ram, Kristipati Ravi AU - Rand, David AU - Rasmussen, Matthew AU - Reed, Laura AU - Reenan, Robert AU - Reily, Amy AU - Remington, Karin AU - Rieger, Tania AU - Ritchie, Michael AU - Robin, Charles AU - Rogers, Yu-Hui AU - Rohde, Claudia AU - Rozas, Julio AU - Rubenfield, Marc AU - Ruiz, Alfredo AU - Russo, Susan AU - Salzberg, Steven AU - Sanchez-Gracia, Alejandro AU - Saranga, David AU - Sato, Hajime AU - Schaeffer, Stephen AU - Schatz, Michael AU - Schlenke, Todd AU - Schwartz, Russell AU - Segarra, Carmen AU - Singh, Rama AU - Sirot, Laura AU - Sirota, Marina AU - Sisneros, Nicholas AU - Smith, Chris AU - Smith, Temple AU - Spieth, John AU - Stage, Deborah AU - Stark, Alexander AU - Stephan, Wolfgang AU - Strausberg, Robert AU - Strempel, Sebastian AU - Sturgill, David AU - Sutton, Granger AU - Sutton, Granger AU - Tao, Wei AU - Teichmann, Sarah AU - Tobari, Yoshiko AU - Tomimura, Yoshihiko AU - Tsolas, Jason AU - Valente, Vera AU - Venter, Eli AU - Venter, Craig AU - Vicario, Saverio AU - Vieira, Filipe AU - Vilella, Albert AU - Villasante, Alfredo AU - Walenz, Brian AU - Wang, Jun AU - Wasserman, Marvin AU - Watts, Thomas AU - Wilson, Derek AU - Wilson, Richard AU - Wing, Rod AU - Wolfner, Mariana AU - Wong, Alex AU - Wong, Gane Ka-Shu AU - Wu, Chung-I AU - Wu, Gabriel AU - Yamamoto, Daisuke AU - Yang, Hsiao-Pei AU - Yang, Shiaw-Pyng AU - Yorke, James AU - Yoshida, Kiyohito AU - Zdobnov, Evgeny AU - Zhang, Peili AU - Zhang, Yu AU - Zimin, Aleksey AU - Baldwin, Jennifer AU - Abdouelleil, Amr AU - Abdulkadir, Jamal AU - Abebe, Adal AU - Abera, Brikti AU - Abreu, Justin AU - Acer, St Christophe AU - Aftuck, Lynne AU - Alexander, Allen AU - An, Peter AU - Anderson, Erica AU - Anderson, Scott AU - Arachi, Harindra AU - Azer, Marc AU - Bachantsang, Pasang AU - Barry, Andrew AU - Bayul, Tashi AU - Berlin, Aaron AU - Bessette, Daniel AU - Bloom, Toby AU - Blye, Jason AU - Boguslavskiy, Leonid AU - Bonnet, Claude AU - Boukhgalter, Boris AU - Bourzgui, Imane AU - Brown, Adam AU - Cahill, Patrick AU - Channer, Sheridon AU - Cheshatsang, Yama AU - Chuda, Lisa AU - Citroen, Mieke AU - Collymore, Alville AU - Cooke, Patrick AU - Costello, Maura AU - D'Aco, Katie AU - Daza, Riza AU - De Haan, Georgius AU - DeGray, Stuart AU - DeMaso, Christina AU - Dhargay, Norbu AU - Dooley, Kimberly AU - Dooley, Erin AU - Doricent, Missole AU - Dorje, Passang AU - Dorjee, Kunsang AU - Dupes, Alan AU - Elong, Richard AU - Falk, Jill AU - Farina, Abderrahim AU - Faro, Susan AU - Ferguson, Diallo AU - Fisher, Sheila AU - Foley, Chelsea AU - Franke, Alicia AU - Friedrich, Dennis AU - Gadbois, Loryn AU - Gearin, Gary AU - Gearin, Christina AU - Giannoukos, Georgia AU - Goode, Tina AU - Graham, Joseph AU - Grandbois, Edward AU - Grewal, Sharleen AU - Gyaltsen, Kunsang AU - Hafez, Nabil AU - Hagos, Birhane AU - Hall, Jennifer AU - Henson, Charlotte AU - Hollinger, Andrew AU - Honan, Tracey AU - Huard, Monika AU - Hughes, Leanne AU - Hurhula, Brian AU - Husby, Erii AU - Kamat, Asha AU - Kanga, Ben AU - Kashin, Seva AU - Khazanovich, Dmitry AU - Kisner, Peter AU - Lance, Krista AU - Lara, Marcia AU - Lee, William AU - Lennon, Niall AU - Letendre, Frances AU - LeVine, Rosie AU - Lipovsky, Alex AU - Liu, Xiaohong AU - Liu, Jinlei AU - Liu, Shangtao AU - Lokyitsang, Tashi AU - Lokyitsang, Yeshi AU - Lubonja, Rakela AU - Lui, Annie AU - MacDonald, Pen AU - Magnisalis, Vasilia AU - Maru, Kebede AU - Matthews, Charles AU - McCusker, William AU - McDonough, Susan AU - Mehta, Teena AU - Meldrim, James AU - Meneus, Louis AU - Mihai, Oana AU - Mihalev, Atanas AU - Mihova, Tanya AU - Mittelman, Rachel AU - Mlenga, Valentine AU - Montmayeur, Anna AU - Mulrain, Leonidas AU - Navidi, Adam AU - Naylor, Jerome AU - Negash, Tamrat AU - Nguyen, Thu AU - Nguyen, Nga AU - Nicol, Robert AU - Norbu, Choe AU - Norbu, Nyima AU - Novod, Nathaniel AU - O'Neill, Barry AU - Osman, Sahal AU - Markiewicz, Eva AU - Oyono, Otero AU - Patti, Christopher AU - Phunkhang, Pema AU - Pierre, Fritz AU - Priest, Margaret AU - Raghuraman, Sujaa AU - Rege, Filip AU - Reyes, Rebecca AU - Rise, Cecil AU - Rogov, Peter AU - Ross, Keenan AU - Ryan, Elizabeth AU - Settipalli, Sampath AU - Shea, Terry AU - Sherpa, Ngawang AU - Shi, Lu AU - Shih, Diana AU - Sparrow, Todd AU - Spaulding, Jessica AU - Stalker, John AU - Stange-Thomann, Nicole AU - Stavropoulos, Sharon AU - Stone, Catherine AU - Strader, Christopher AU - Tesfaye, Senait AU - Thomson, Talene AU - Thoulutsang, Yama AU - Thoulutsang, Dawa AU - Topham, Kerri AU - Topping, Ira AU - Tsamla, Tsamla AU - Vassiliev, Helen AU - Vo, Andy AU - Wangchuk, Tsering AU - Wangdi, Tsering AU - Weiand, Michael AU - Wilkinson, Jane AU - Wilson, Adam AU - Yadav, Shailendra AU - Young, Geneva AU - Yu, Qing AU - Zembek, Lisa AU - Zhong, Danni AU - Zimmer, Andrew AU - Zwirko, Zac AU - Jaffe, David AU - Alvarez, Pablo AU - Brockman, Will AU - Butler, Jonathan AU - Chin, CheeWhye AU - Gnerre, Sante AU - Grabherr, Manfred AU - Kleber, Michael AU - Mauceli, Evan AU - MacCallum, Iain PY - 2007/11/08/ UR - http://dx.doi.org/10.1038/nature06341 ER -