[Reconstruction of ancestral regulatory signals along a transcription factor tree] Export

@article{citeulike:2634252, abstract = {A model and an algorithm are proposed to reconstruct ancestral regulatory signals, mostly of protein-DNA interaction, at inner nodes of the transcription factor phylogeny on the basis of contemporary signal distribution. The algorithm also infers an evolutionary scenario, i.e. a set of edges in the tree, along which the signal diverged the most. The model and algorithm were tested with artificial data and biological evidence on signals NrdR, MntR and factor LacI (for the last two cases data are not shown).}, author = {Gorbunov, K. I. u. and Liubetski\u{i}\u{i}, V. A.}, citeulike-article-id = {2634252}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/18240574}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=18240574}, issn = {0026-8984}, journal = {Molekuliarnaia biologiia}, keywords = {ancestor, crm, evolution, grn}, number = {5}, pages = {918--925}, posted-at = {2008-07-01 17:02:01}, priority = {2}, title = {[Reconstruction of ancestral regulatory signals along a transcription factor tree]}, url = {http://view.ncbi.nlm.nih.gov/pubmed/18240574}, volume = {41}, year = {2007} }

TY - JOUR ID - citeulike:2634252 L3 - citeulike-article-id:2634252 N2 - A model and an algorithm are proposed to reconstruct ancestral regulatory signals, mostly of protein-DNA interaction, at inner nodes of the transcription factor phylogeny on the basis of contemporary signal distribution. The algorithm also infers an evolutionary scenario, i.e. a set of edges in the tree, along which the signal diverged the most. The model and algorithm were tested with artificial data and biological evidence on signals NrdR, MntR and factor LacI (for the last two cases data are not shown). IS - 5 JF - Molekuliarnaia biologiia SN - 0026-8984 EP - 925 TI - [Reconstruction of ancestral regulatory signals along a transcription factor tree] VL - 41 SP - 918 KW - ancestor KW - crm KW - evolution KW - grn AU - Gorbunov, KIu AU - Liubetskiĭĭ, VA PY - 2007///t UR - http://view.ncbi.nlm.nih.gov/pubmed/18240574 ER -