An MRI study of pituitary volume and parasuicidal behavior in teenagers with first-presentation borderline personality disorder

@article{citeulike:2721737, abstract = {This structural magnetic resonance imaging study examined the relationship between pituitary gland volume (PGV) and lifetime number of parasuicidal behaviors in a first-presentation, teenage borderline personality disorder (BPD) sample with minimal exposure to treatment. Hierarchical regression analysis revealed that age and number of parasuicidal behaviors were significant predictors of PGV. These findings indicate that parasuicidal behavior in BPD might be associated with greater activation of the hypothalamic-pituitary-adrenal (HPA) axis. Further studies are required using direct neuroendocrine measures and exploring other parameters of self-injurious behavior, such as recency of self-injurious behavior, intent to die and medical threat.}, author = {Jovev, Martina and Garner, Belinda and Phillips, Lisa and Velakoulis, Dennis and Wood, Stephen J. and Jackson, Henry J. and Pantelis, Christos and Mcgorry, Patrick D. and Chanen, Andrew M. }, citeulike-article-id = {2721737}, doi = {10.1016/j.pscychresns.2007.12.003}, journal = {Psychiatry Research: Neuroimaging}, keywords = {borderline, imaging, self-injury, suicide}, month = {April}, number = {3}, pages = {273--277}, posted-at = {2008-04-26 14:14:21}, priority = {2}, title = {An MRI study of pituitary volume and parasuicidal behavior in teenagers with first-presentation borderline personality disorder}, url = {http://dx.doi.org/10.1016/j.pscychresns.2007.12.003}, volume = {162}, year = {2008} }

TY - JOUR ID - citeulike:2721737 L3 - citeulike-article-id:2721737 TI - An MRI study of pituitary volume and parasuicidal behavior in teenagers with first-presentation borderline personality disorder JF - Psychiatry Research: Neuroimaging VL - 162 IS - 3 SP - 273 EP - 277 N2 - This structural magnetic resonance imaging study examined the relationship between pituitary gland volume (PGV) and lifetime number of parasuicidal behaviors in a first-presentation, teenage borderline personality disorder (BPD) sample with minimal exposure to treatment. Hierarchical regression analysis revealed that age and number of parasuicidal behaviors were significant predictors of PGV. These findings indicate that parasuicidal behavior in BPD might be associated with greater activation of the hypothalamic-pituitary-adrenal (HPA) axis. Further studies are required using direct neuroendocrine measures and exploring other parameters of self-injurious behavior, such as recency of self-injurious behavior, intent to die and medical threat. KW - borderline KW - imaging KW - self-injury KW - suicide AU - Jovev, Martina AU - Garner, Belinda AU - Phillips, Lisa AU - Velakoulis, Dennis AU - Wood, Stephen AU - Jackson, Henry AU - Pantelis, Christos AU - Mcgorry, Patrick AU - Chanen, Andrew PY - 2008/04/15/ UR - http://dx.doi.org/10.1016/j.pscychresns.2007.12.003 ER -