Molecular landmarks along the axonal route: axonal transport in health and disease Export

@article{citeulike:2896616, abstract = {Axonal transport of organelles has emerged as a key process in the regulation of neuronal differentiation and survival. Several components of this specialised transport machinery, their regulators and vesicular cargoes are mutated or altered in many neurodegenerative conditions. The molecular characterisation of these mechanisms has furthered our understanding of neuronal homeostasis, providing insights into the spatio-temporal control of membrane traffic and signalling in neurons with a precision not achievable in other cellular systems. Here, we summarise the recent advances in the field of axonal trafficking of different organelles, and the essential role of motor and adaptor proteins in this process.}, author = {Salinas, Sara and Bilsland, Lynsey G. and Schiavo, Giampietro}, citeulike-article-id = {2896616}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ceb.2008.04.002}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0955067408000732}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/18495455}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=18495455}, citeulike-linkout-4 = {http://www.sciencedirect.com/science/article/B6VRW-4SJF1JR-2/1/45fcd54e7e82a524bd9a7a65315367af}, doi = {10.1016/j.ceb.2008.04.002}, journal = {Current Opinion in Cell Biology}, keywords = {cell\_bio}, posted-at = {2008-06-15 21:30:48}, priority = {2}, title = {Molecular landmarks along the axonal route: axonal transport in health and disease}, url = {http://dx.doi.org/10.1016/j.ceb.2008.04.002}, volume = {In Press, Corrected Proof} }

TY - JOUR ID - citeulike:2896616 L3 - citeulike-article-id:2896616 N2 - Axonal transport of organelles has emerged as a key process in the regulation of neuronal differentiation and survival. Several components of this specialised transport machinery, their regulators and vesicular cargoes are mutated or altered in many neurodegenerative conditions. The molecular characterisation of these mechanisms has furthered our understanding of neuronal homeostasis, providing insights into the spatio-temporal control of membrane traffic and signalling in neurons with a precision not achievable in other cellular systems. Here, we summarise the recent advances in the field of axonal trafficking of different organelles, and the essential role of motor and adaptor proteins in this process. JF - Current Opinion in Cell Biology TI - Molecular landmarks along the axonal route: axonal transport in health and disease VL - In Press, Corrected Proof KW - cell_bio AU - Salinas, Sara AU - Bilsland, Lynsey AU - Schiavo, Giampietro UR - http://dx.doi.org/10.1016/j.ceb.2008.04.002 ER -