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psique's synuclein [48 articles]

Recent papers added to psique's library classified by the tag synuclein. You can also see everyone's synuclein.
  • Analysis of Parkinson disease patients from Portugal for mutations in SNCA, PRKN, PINK1 and LRRK2
    BMC Neurology, Vol. 8 (22 January 2008), 1.
    by Jose Bras, Rita Guerreiro, Maria Ribeiro, Ana Morgadinho, Cristina Januario, Margarida Dias, Ana Calado, Cristina Semedo, Catarina Oliveira, John Hardy, Andrew Singleton
    posted to synuclein pink1 pd parkin lrrk2 by psique on 2008-09-18 13:13:31 as *** along with 1 group parkinson's disease references
  • A unifying hypothesis for explaining the mechanism of amyloid formation under conditions of increased oxidative stress
    Bioscience Hypotheses, Vol. In Press, Corrected Proof
    by Ayse A Aydemir-Koksoy
    posted to pd synuclein amyloid ad by psique on 2008-09-17 13:51:57 as **** along with 1 group parkinson's disease references
  • alpha-Synuclein locus triplication causes Parkinson's disease.
    Science (New York, N.Y.), Vol. 302, No. 5646. (31 October 2003)
    by AB Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, M Hulihan, T Peuralinna, A Dutra, R Nussbaum, S Lincoln, A Crawley, M Hanson, D Maraganore, C Adler, MR Cookson, M Muenter, M Baptista, D Miller, J Blancato, J Hardy, K Gwinn-Hardy
    posted to synuclein pd cnv by psique on 2008-09-15 11:36:32 as read along with 1 group parkinson's disease references
  • Brain reward in the absence of alpha-synuclein.
    Neuroreport, Vol. 17, No. 11. (31 July 2006), pp. 1191-1194.
    by M Oksman, H Tanila, L Yavich
    posted to da dbs synuclein by psique on 2008-08-25 15:53:17 as ** along with 1 group parkinson's disease references
  • Alpha-synuclein and Parkinson's disease: implications from the screening of more than 1,900 patients.
    Movement disorders : official journal of the Movement Disorder Society, Vol. 20, No. 9. (September 2005), pp. 1191-1194.
    by D Berg, M Niwar, S Maass, A Zimprich, JC Möller, U Wuellner, T Schmitz-Hübsch, C Klein, EK Tan, L Schöls, L Marsh, TM Dawson, B Janetzky, T Müller, D Woitalla, V Kostic, PP Pramstaller, WH Oertel, P Bauer, R Krueger, T Gasser, O Riess
    posted to pd synuclein by psique on 2008-06-20 10:53:38 as ** along with 1 group parkinson's disease references
  • Human-based studies on alpha-synuclein deposition and relationship to Parkinson's disease symptoms.
    Experimental neurology, Vol. 209, No. 1. (January 2008), pp. 12-21.
    by GM Halliday, H McCann
    posted to pd synuclein by psique on 2008-06-12 19:03:10 as **** along with 1 group parkinson's disease references
  • In vivo alpha-synuclein overexpression in rodents: a useful model of Parkinson's disease?
    Experimental neurology, Vol. 209, No. 1. (January 2008), pp. 22-27.
    by MF Chesselet
    posted to pd synuclein by psique on 2008-06-12 19:01:35 as ** along with 1 group parkinson's disease references
  • Alpha-synuclein haplotypes implicated in risk of Parkinson's disease.
    Neurology, Vol. 62, No. 1. (13 January 2004), pp. 128-131.
    by EK Tan, A Chai, YY Teo, Y Zhao, C Tan, H Shen, VR Chandran, ML Teoh, Y Yih, R Pavanni, MC Wong, K Puvan, YL Lo, E Yap
    posted to snp synuclein by psique on 2008-06-11 22:27:16 as ** along with 1 group parkinson's disease references
  • Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.
    JAMA : the journal of the American Medical Association, Vol. 296, No. 6. (9 August 2006), pp. 661-670.
    by DM Maraganore, M de Andrade, A Elbaz, MJ Farrer, JP Ioannidis, R Krüger, WA Rocca, NK Schneider, TG Lesnick, SJ Lincoln, MM Hulihan, JO Aasly, T Ashizawa, MC Chartier-Harlin, H Checkoway, C Ferrarese, G Hadjigeorgiou, N Hattori, H Kawakami, JC Lambert, T Lynch, GD Mellick, S Papapetropoulos, A Parsian, A Quattrone, O Riess, EK Tan, C Van Broeckhoven,
    posted to snp pd synuclein by psique on 2008-06-11 22:15:04 as read along with 1 group parkinson's disease references
  • alpha-Synuclein promoter confers susceptibility to Parkinson's disease.
    Annals of neurology, Vol. 56, No. 4. (October 2004), pp. 591-595.
    by P Pals, S Lincoln, J Manning, M Heckman, L Skipper, M Hulihan, M Van den Broeck, T De Pooter, P Cras, J Crook, C Van Broeckhoven, MJ Farrer
    posted to snp pd synuclein by psique on 2008-06-11 22:10:27 as read along with 1 group parkinson's disease references
  • Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy.
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 2. (18 January 2000), pp. 571-576.
    by KA Conway, SJ Lee, JC Rochet, TT Ding, RE Williamson, PT Lansbury
    posted to pd synuclein by psique on 2008-06-11 21:06:56 as ** along with 1 group parkinson's disease references
  • A protein-chameleon: conformational plasticity of alpha-synuclein, a disordered protein involved in neurodegenerative disorders.
    Journal of biomolecular structure & dynamics, Vol. 21, No. 2. (October 2003), pp. 211-234.
    by VN Uversky
    posted to synuclein by psique on 2008-06-11 20:47:33 as ** along with 1 group parkinson's disease references
  • Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders.
    Science (New York, N.Y.), Vol. 287, No. 5456. (18 February 2000), pp. 1265-1269.
    by E Masliah, E Rockenstein, I Veinbergs, M Mallory, M Hashimoto, A Takeda, Y Sagara, A Sisk, L Mucke
    posted to da pd synuclein by psique on 2008-06-11 20:35:41 as read along with 1 group parkinson's disease references
  • Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, No. 42. (20 October 2004), pp. 9434-9440.
    by SM Fleming, J Salcedo, PO Fernagut, E Rockenstein, E Masliah, MS Levine, MF Chesselet
    posted to pd synuclein by psique on 2008-06-11 20:21:00 as ** along with 1 group parkinson's disease references
  • DJ-1 Is a Redox-Dependent Molecular Chaperone That Inhibits α-Synuclein Aggregate Formation
    PLoS Biology, Vol. 2, No. 11. (1 November 2004), e362.
    by Shoshana Shendelman, Alan Jonason, Cecile Martinat, Thomas Leete, Asa Abeliovich
    posted to pd dj-1 synuclein by psique on 2008-06-10 20:23:03 as ** along with 1 group parkinson's disease references
  • Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level
    PLoS Biology, Vol. 6, No. 1. (1 January 2008), e6.
    by Massimo Sandal, Francesco Valle, Isabella Tessari, Stefano Mammi, Elisabetta Bergantino, Francesco Musiani, Marco Brucale, Luigi Bubacco, Bruno Samorì
    posted to structure synuclein by psique on 2008-06-10 19:48:21 as **** along with 1 group parkinson's disease references
  • The [alpha]-synuclein burden hypothesis of Parkinson disease and its relationship to Alzheimer disease
    Experimental Neurology, Vol. In Press, Corrected Proof
    by Patrick L Mcgeer, Edith G Mcgeer
    posted to pd ad synuclein by psique on 2008-06-04 18:21:20 as read along with 1 group parkinson's disease references
  • Alpha-synuclein: normal function and role in neurodegenerative diseases.
    Current topics in developmental biology, Vol. 60 (2004), pp. 17-54.
    by EH Norris, BI Giasson, VM Lee
    posted to pd synuclein by psique on 2008-06-03 19:15:18 as ** along with 1 group parkinson's disease references
  • Developmental expression of [alpha]-synuclein in rat hippocampus and cerebral cortex
    Neuroscience, Vol. 91, No. 2. (June 1999), pp. 651-659.
    by K Petersen, OF Olesen, JD Mikkelsen
    posted to synuclein by psique on 2008-06-03 19:14:46 as ** along with 1 group parkinson's disease references
  • The cell biology of α-synuclein
    NeuroMolecular Medicine, Vol. 1, No. 2. (4 April 2002), pp. 95-109.
    by Nelson Cole, Diane Murphy
    posted to pd synuclein by psique on 2008-06-03 19:11:15 as *** along with 1 group parkinson's disease references
  • Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
    Human Molecular Genetics (April 2001), pp. 919-926.
    by CA Ross, Y Tanaka, S Engelender, S Igarashi, RK Rao, T Wanner, RE Tanzi, A Sawa, Dawson, TM Dawson
    posted to pd mitochondria synuclein ups by psique on 2008-06-03 19:10:35 as *** along with 1 group parkinson's disease references
  • notes Membrane binding and self-association of alpha-synucleins.
    Biochemistry, Vol. 40, No. 33. (21 August 2001), pp. 9927-9934.
    by V Narayanan, S Scarlata
    posted to synuclein by psique on 2008-06-03 19:08:26 as *** along with 1 group parkinson's disease references
  • Expression of alpha-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes associated with familial Parkinson's disease
    Annals of Neurology, Vol. 47, No. 2. (26 April 2001), pp. 201-210.
    by Solano, Miller, Augood, Young, Penney
    posted to pd parkin synuclein uchl1 by psique on 2008-06-03 19:05:11 as read along with 1 group parkinson's disease references
  • Molecular mechanisms of selective dopaminergic neuronal death in Parkinson's disease
    Trends in Molecular Medicine, Vol. 9, No. 3. (March 2003), pp. 126-132.
    by Ari Barzilai, Eldad Melamed
    posted to da pd synuclein by psique on 2008-06-02 22:04:33 as read along with 1 group parkinson's disease references
  • Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers.
    Acta neuropathologica, Vol. 112, No. 3. (September 2006), pp. 237-251.
    by K Beyer
    posted to pd phosphorylation structure synuclein by psique on 2008-06-02 07:55:23 as read along with 1 group parkinson's disease references
  • The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease
    Trends in Neurosciences, Vol. 21, No. 6. (1 June 1998), pp. 249-254.
    by David F Clayton, Julia M George
    posted to pd synuclein by psique on 2008-05-28 22:28:58 as read along with 1 group parkinson's disease references
  • The biochemistry of Parkinson's disease.
    Annu Rev Biochem, Vol. 74 (2005), pp. 29-52.
    by MR Cookson
    posted to da pd dj-1 parkin pink1 synuclein by psique on 2008-05-28 22:25:27 as read along with 1 person lenov
  • Neuropathological spectrum of synucleinopathies.
    Movement disorders : official journal of the Movement Disorder Society, Vol. 18 Suppl 6 (September 2003)
    by KA Jellinger
    posted to pd msa synuclein by psique on 2008-05-28 17:08:43 as read along with 1 group parkinson's disease references
  • The role of α-synuclein in the pathogenesis of multiple system atrophy
    Acta Neuropathologica, Vol. 109, No. 2. (5 February 2005), pp. 129-140.
    by Gregor K Wenning, Kurt A Jellinger
    posted to msa synuclein by psique on 2008-05-28 17:07:56 as read along with 1 group parkinson's disease references
  • neuropathology of synuclein aggregates
    journal of neuroscience research, Vol. 61, No. 2. (2000), pp. 121-127.
    by JE Duda, My V Lee, JQ Trojanowski
    posted to pd msa synuclein by psique on 2008-05-28 17:05:45 as ** along with 1 group parkinson's disease references
  • Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.
    Nature genetics, Vol. 18, No. 2. (February 1998), pp. 106-108.
    by R Krüger, W Kuhn, T Müller, D Woitalla, M Graeber, S Kösel, H Przuntek, JT Epplen, L Schöls, O Riess
    posted to pd synuclein by psique on 2008-05-28 17:02:41 as read along with 1 group parkinson's disease references
  • Enhanced vulnerability to oxidative stress by [alpha]-synuclein mutations and C-terminal truncation
    Neuroscience, Vol. 97, No. 2. (April 2000), pp. 279-284.
    by S Kanda, JF Bishop, MA Eglitis, Y Yang, MM Mouradian
    posted to oxidative_stress synuclein by psique on 2008-05-28 17:01:31 as read along with 1 group parkinson's disease references
  • Cellular pathology of multiple system atrophy: a review.
    Journal of neurology, neurosurgery, and psychiatry, Vol. 57, No. 2. (February 1994), pp. 129-133.
    by PL Lantos, MI Papp
    posted to msa synuclein by psique on 2008-05-28 16:58:51 as read along with 1 group parkinson's disease references
  • Conformational properties of alpha-synuclein in its free and lipid-associated states.
    Journal of molecular biology, Vol. 307, No. 4. (6 April 2001), pp. 1061-1073.
    by D Eliezer, E Kutluay, R Bussell, G Browne
    posted to structure synuclein by psique on 2008-05-27 16:25:07 as ** along with 1 group parkinson's disease references
  • Whole genome expression analyses of single- and double-knock-out mice implicate partially overlapping functions of alpha- and gamma-synuclein
    Neurogenetics, Vol. 8, No. 2. (April 2007), pp. 71-81.
    by Kuhn, Melanie, Haebig, Karina, Bonin, Michael, Ninkina, Natalia, Buchman, Vladimir, Poths, Sven, Riess, Olaf
    posted to synuclein by psique on 2008-05-27 16:19:33 as read along with 1 group parkinson's disease references
  • Synucleins Are Developmentally Expressed, and alpha -Synuclein Regulates the Size of the Presynaptic Vesicular Pool in Primary Hippocampal Neurons
    J. Neurosci., Vol. 20, No. 9. (1 May 2000), pp. 3214-3220.
    by Diane D Murphy, Susan M Rueter, John Q Trojanowski, Virginia M Lee
    posted to synuclein by psique on 2008-05-27 16:16:56 as read along with 1 group parkinson's disease references
  • alpha -Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins
    J. Neurosci., Vol. 19, No. 14. (15 July 1999), pp. 5782-5791.
    by Natalie Ostrerova, Leonard Petrucelli, Matthew Farrer, Nitinkumar Mehta, Peter Choi, John Hardy, Benjamin Wolozin
    posted to pd synuclein by psique on 2008-05-27 16:11:01 as *** along with 1 group parkinson's disease references
  • Assignment of Human [alpha]-Synuclein (SNCA) and [beta]-Synuclein (SNCB) Genes to Chromosomes 4q21 and 5q35
    Genomics, Vol. 27, No. 2. (20 May 1995), pp. 379-381.
    by Maria G Spillantini, Aspasia Divane, Michel Goedert
    posted to pd genomics synuclein by psique on 2008-05-27 16:08:31 as **** along with 1 group parkinson's disease references
  • Alpha-synuclein in Lewy bodies.
    Nature, Vol. 388, No. 6645. (28 August 1997), pp. 839-840.
    by MG Spillantini, ML Schmidt, VM Lee, JQ Trojanowski, R Jakes, M Goedert
    posted to pd synuclein by psique on 2008-05-27 16:03:37 as **** along with 1 group parkinson's disease references
  • Helical alpha-Synuclein Forms Highly Conductive Ion Channels
    Biochemistry (22 November 2007)
    by SD Zakharov, JD Hulleman, EA Dutseva, YN Antonenko, JC Rochet, WA Cramer
    posted to structure synuclein by psique on 2008-05-07 08:40:23 as read along with 1 person and 1 group paulschlesinger parkinson's disease references
  • A neuroprotective role for α-synuclein
    Nature Reviews Neuroscience, Vol. 7, No. 1., pp. 5-5.
    by Daniel Mcgowan
    posted to neuroprotection synuclein by psique on 2008-05-07 08:34:09 as *** along with 1 group parkinson's disease references
  • Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes.
    The Journal of biological chemistry, Vol. 273, No. 16. (17 April 1998), pp. 9443-9449.
    by WS Davidson, A Jonas, DF Clayton, JM George
    posted to structure synuclein by psique on 2008-05-07 08:32:29 as read along with 1 group parkinson's disease references
  • Membrane-bound structure and energetics of alpha-synuclein
    Proteins: Structure, Function, and Bioinformatics, Vol. 70, No. 3. (2008), pp. 761-778.
    by Maja Mihajlovic, Themis Lazaridis
    posted to structure synuclein by psique on 2008-05-07 08:27:24 as **** along with 1 person and 1 group paulschlesinger parkinson's disease references
  • Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, No. 20. (15 October 2002), pp. 8797-8807.
    by DE Cabin, K Shimazu, D Murphy, NB Cole, W Gottschalk, KL McIlwain, B Orrison, A Chen, CE Ellis, R Paylor, B Lu, RL Nussbaum
    posted to hippocampus synuclein by psique on 2008-05-07 08:17:07 as read along with 1 group parkinson's disease references
  • Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein.
    Nature reviews. Neuroscience, Vol. 3, No. 12. (December 2002), pp. 932-942.
    by J Lotharius, P Brundin
    posted to da pd synuclein by psique on 2008-05-07 08:01:43 as read along with 1 group parkinson's disease references
  • Mice Lacking [alpha]-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System
    Neuron, Vol. 25, No. 1. (January 2000), pp. 239-252.
    by Asa Abeliovich, Yvonne Schmitz, Isabel Fariñas, Derek Choi-Lundberg, Wei-Hsien Ho, Pablo E Castillo, Natasha Shinsky, Jose M Verdugo, Mark Armanini, Anne Ryan, Mary Hynes, Heidi Phillips, David Sulzer, Arnon Rosenthal
    posted to da synuclein by psique on 2008-05-07 07:58:45 as read along with 1 group parkinson's disease references
  • Structure/function of alpha-synuclein in health and disease: rational development of animal models for Parkinson's and related diseases
    Journal of Neurochemistry, Vol. 82, No. 3. (2002), pp. 449-457.
    by Philipp J Kahle, Christian Haass, Hans A Kretzschmar, Manuela Neumann
    posted to pd synuclein by psique on 2008-05-07 07:52:45 as read along with 1 group parkinson's disease references
  • Characterization of Conformational and Dynamic Properties of Natively Unfolded Human and Mouse [alpha]-Synuclein Ensembles by NMR: Implication for Aggregation
    Journal of Molecular Biology, Vol. 378, No. 5. (16 May 2008), pp. 1104-1115.
    by Kuen-Phon Wu, Seho Kim, David A Fela, Jean Baum
    posted to pd synuclein by psique on 2008-04-29 19:53:31 as ** along with 1 group parkinson's disease references
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