Environmental covariates: Effects on the power of sib-pair linkage methods Export

@article{mandal99:covar, abstract = {The effect of inclusion of environmental risk factors on the power of sib-pair linkage methods was tested for a qualitative trait. It was found that inclusion of an environmental variable did not increase the power of the Haseman-Elston (H-E) sib-pair nonparametric linkage analysis test. However, a significant increase in power was observed for both the H-E and affected- sib-pair tests, even in small samples, when persons unexposed to the environmental risk factor were coded as unknown. (C) 1999 Wiley-Liss, Inc.}, annote = {genetics; sib-pair; linkage; covariates}, author = {Mandal, D. M. and Sorant, A. J. M. and Pugh, E. W. and Marcus, S. E. and Klein, A. P. and Mathias, R. A. and O'Neill, J. and Temiyakarn, L. F. and Wilson, A. F. and Wilson, Bailey J. E.}, citeulike-article-id = {1437391}, keywords = {affected-sib-pair, combinedbib, complex, linkage, sib-pair, test, traits}, pages = {S643--S648}, posted-at = {2007-07-05 14:55:18}, priority = {2}, title = {Environmental covariates: Effects on the power of sib-pair linkage methods}, volume = {17}, year = {1999} }

TY - JOUR ID - mandal99:covar L3 - citeulike-article-id:1437391 N2 - The effect of inclusion of environmental risk factors on the power of sib-pair linkage methods was tested for a qualitative trait. It was found that inclusion of an environmental variable did not increase the power of the Haseman-Elston (H-E) sib-pair nonparametric linkage analysis test. However, a significant increase in power was observed for both the H-E and affected- sib-pair tests, even in small samples, when persons unexposed to the environmental risk factor were coded as unknown. (C) 1999 Wiley-Liss, Inc. EP - S648 TI - Environmental covariates: Effects on the power of sib-pair linkage methods VL - 17 SP - S643 KW - affected-sib-pair KW - combinedbib KW - complex KW - linkage KW - sib-pair KW - test KW - traits AU - Mandal, DM AU - Sorant, AJM AU - Pugh, EW AU - Marcus, SE AU - Klein, AP AU - Mathias, RA AU - O'Neill, J AU - Temiyakarn, LF AU - Wilson, AF AU - Wilson, Bailey PY - 1999/// ER -