Fundamental concepts in genetics: Genetics and the understanding of selection Export

@article{citeulike:3847656, abstract = {At first sight selection is a simple notion, and some consider it the most important evolutionary force. But how important is selection, is it really so trivial to understand and what are the alternatives? Here I discuss how genetics is crucial for addressing all of these questions: genetics allowed the concept of natural selection to become viable, it contributed to our understanding of the complexities of selection and it spurred the development of competing models of evolution. Understanding how and why selection acts has important potential applications, from understanding the mechanisms of disease and microbial resistance, to improving the design of transgenes and drugs.}, author = {Hurst, Laurence D.}, citeulike-article-id = {3847656}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrg2506}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrg2506}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/19119264}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=19119264}, day = {01}, doi = {10.1038/nrg2506}, issn = {1471-0056}, journal = {Nature Reviews Genetics}, keywords = {evolution, genetic, learning}, month = {February}, number = {2}, pages = {83--93}, posted-at = {2009-05-10 16:11:05}, priority = {2}, publisher = {Nature Publishing Group}, title = {Fundamental concepts in genetics: Genetics and the understanding of selection}, url = {http://dx.doi.org/10.1038/nrg2506}, volume = {10}, year = {2009} }

TY - JOUR ID - citeulike:3847656 L3 - citeulike-article-id:3847656 N2 - At first sight selection is a simple notion, and some consider it the most important evolutionary force. But how important is selection, is it really so trivial to understand and what are the alternatives? Here I discuss how genetics is crucial for addressing all of these questions: genetics allowed the concept of natural selection to become viable, it contributed to our understanding of the complexities of selection and it spurred the development of competing models of evolution. Understanding how and why selection acts has important potential applications, from understanding the mechanisms of disease and microbial resistance, to improving the design of transgenes and drugs. IS - 2 JF - Nature Reviews Genetics SN - 1471-0056 EP - 93 TI - Fundamental concepts in genetics: Genetics and the understanding of selection PB - Nature Publishing Group VL - 10 SP - 83 KW - evolution KW - genetic KW - learning AU - Hurst, Laurence PY - 2009/02/01/ UR - http://dx.doi.org/10.1038/nrg2506 ER -