The Structure and Function of Mitochondrial F1F0‐ATP Synthases Export

@inbook{citeulike:4501176, abstract = {We review recent advances in understanding of the structure of the F 1 F 0 -ATP synthase of the mitochondrial inner membrane (mtATPase). A significant achievement has been the determination of the structure of the principal peripheral or stator stalk components bringing us closer to achieving the Holy Grail of a complete 3D structure for the complex. A major focus of the field in recent years has been to understand the physiological significance of dimers or other oligomer forms of mtATPase recoverable from membranes and their relationship to the structure of the cristae of the inner mitochondrial membrane. In addition, the association of mtATPase with other membrane proteins has been described and suggests that further levels of functional organization need to be considered. Many reports in recent years have concerned the location and function of ATP synthase complexes or its component subunits on the external surface of the plasma membrane. We consider whether the evidence supports complete complexes being located on the cell surface, the biogenesis of such complexes, and aspects of function especially related to the structure of mtATPase.}, author = {Devenish, Rodney J. and Prescott, Mark and Rodgers, Andrew J.}, booktitle = {International Review of Cell and Molecular Biology Volume 267}, citeulike-article-id = {4501176}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/S1937-6448(08)00601-1}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S1937644808006011}, doi = {10.1016/S1937-6448(08)00601-1}, issn = {19376448}, keywords = {atp6, basis, mitochondria, projmt, review, yeast}, pages = {1--58}, posted-at = {2009-05-10 16:19:53}, priority = {5}, series = {International Review of Cell and Molecular Biology}, title = {The Structure and Function of Mitochondrial F1F0‐ATP Synthases}, url = {http://dx.doi.org/10.1016/S1937-6448(08)00601-1}, volume = {267}, year = {2008} }

TY - CHAP ID - citeulike:4501176 L3 - citeulike-article-id:4501176 N2 - We review recent advances in understanding of the structure of the F 1 F 0 -ATP synthase of the mitochondrial inner membrane (mtATPase). A significant achievement has been the determination of the structure of the principal peripheral or stator stalk components bringing us closer to achieving the Holy Grail of a complete 3D structure for the complex. A major focus of the field in recent years has been to understand the physiological significance of dimers or other oligomer forms of mtATPase recoverable from membranes and their relationship to the structure of the cristae of the inner mitochondrial membrane. In addition, the association of mtATPase with other membrane proteins has been described and suggests that further levels of functional organization need to be considered. Many reports in recent years have concerned the location and function of ATP synthase complexes or its component subunits on the external surface of the plasma membrane. We consider whether the evidence supports complete complexes being located on the cell surface, the biogenesis of such complexes, and aspects of function especially related to the structure of mtATPase. SE - International Review of Cell and Molecular Biology SN - 19376448 EP - 58 TI - The Structure and Function of Mitochondrial F1F0‐ATP Synthases VL - 267 T2 - International Review of Cell and Molecular Biology Volume 267 SP - 1 KW - atp6 KW - basis KW - mitochondria KW - projmt KW - review KW - yeast AU - Devenish, Rodney AU - Prescott, Mark AU - Rodgers, Andrew PY - 2008/// UR - http://dx.doi.org/10.1016/S1937-6448(08)00601-1 ER -