Function and biogenesis of ironâsulphur proteins Export

@article{citeulike:5431902, abstract = {Iron–sulphur (Fe–S) clusters have long been recognized as essential and versatile cofactors of proteins involved in catalysis, electron transport and sensing of ambient conditions. Despite the relative simplicity of Fe–S clusters in terms of structure and composition, their synthesis and assembly into apoproteins is a highly complex and coordinated process in living cells. Different biogenesis machineries in both bacteria and eukaryotes have been discovered that assist Fe–S-protein maturation according to uniform biosynthetic principles. The importance of Fe–S proteins for life is documented by an increasing number of diseases linked to these components and their biogenesis.}, author = {Lill, Roland}, citeulike-article-id = {5431902}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nature08301}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nature08301}, day = {12}, doi = {10.1038/nature08301}, issn = {0028-0836}, journal = {Nature}, keywords = {basis, goodref, mitochondria, projnarp, review, yeast}, month = {August}, number = {7257}, pages = {831--838}, posted-at = {2009-10-05 15:41:35}, priority = {5}, publisher = {Nature Publishing Group}, title = {Function and biogenesis of iron\^{a}€“sulphur proteins}, url = {http://dx.doi.org/10.1038/nature08301}, volume = {460}, year = {2009} }

TY - JOUR ID - citeulike:5431902 L3 - citeulike-article-id:5431902 N2 - Iron–sulphur (Fe–S) clusters have long been recognized as essential and versatile cofactors of proteins involved in catalysis, electron transport and sensing of ambient conditions. Despite the relative simplicity of Fe–S clusters in terms of structure and composition, their synthesis and assembly into apoproteins is a highly complex and coordinated process in living cells. Different biogenesis machineries in both bacteria and eukaryotes have been discovered that assist Fe–S-protein maturation according to uniform biosynthetic principles. The importance of Fe–S proteins for life is documented by an increasing number of diseases linked to these components and their biogenesis. IS - 7257 JF - Nature SN - 0028-0836 EP - 838 TI - Function and biogenesis of iron–sulphur proteins PB - Nature Publishing Group VL - 460 SP - 831 KW - basis KW - goodref KW - mitochondria KW - projnarp KW - review KW - yeast AU - Lill, Roland PY - 2009/08/12/ UR - http://dx.doi.org/10.1038/nature08301 ER -