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✔ Mutant rhodopsin transgene expression on a null background.

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Investigative ophthalmology & visual science, Vol. 42, No. 3. (March 2001), pp. 826-833
by J. M. Frederick, N. V. Krasnoperova, K. Hoffmann, et al.J. Church-Kopish, K. Rüther, K. Howes, J. Lem, W. Baehr
posted to mutant plan project rhodopsin by rana-alghamdi on 2012-11-10 09:53:24 **
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Abstract

To study mechanisms leading to photoreceptor degeneration in mouse models for autosomal dominant retinitis pigmentosa (adRP) based on the rhodopsin P23H mutation. Mice of a transgenic line expressing a rhodopsin triple mutant, V20G, P23H, and P27L (GHL), were mated with rhodopsin (rho) knockout mice. Littermates of various ages and genotypes ...
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