renatomilani's drug [58 articles] Export

Recent papers added to renatomilani's library classified by the tag drug. You can also see everyone's drug.

	Hematology: Dasatinib regimens for patients with chronic myeloid leukemia [My Copy] Nature Reviews Clinical Oncology, Vol. 6, No. 12. (01 December 2009), pp. 680-682. by Francois Guilhot, Lydia Roy posted to review leukemia drug by renatomilani on 2009-12-01 21:30:46 as
	Functional group contributions to drug-receptor interactions. [My Copy] Journal of medicinal chemistry, Vol. 27, No. 12. (December 1984), pp. 1648-1657. by P. R. Andrews, D. J. Craik, J. L. Martin posted to structure receptor interaction function f1000 drug by renatomilani on 2009-11-26 19:01:20 as along with 1 person higueruelo
	AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance [My Copy] Vol. 16, No. 5. (6 November 2009), pp. 401-412. by Thomas O'Hare, William C. Shakespeare, Xiaotian Zhu, et al.Christopher A. Eide, Victor M. Rivera, Frank Wang, Lauren T. Adrian, Tianjun Zhou, Wei-Sheng Huang, Qihong Xu, Chester A. Metcalf, Jeffrey W. Tyner, Marc M. Loriaux, Amie S. Corbin, Scott Wardwell, Yaoyu Ning, Jeffrey A. Keats, Yihan Wang, Raji Sundaramoorthi, Mathew Thomas, Dong Zhou, Joseph Snodgrass, Lois Commodore, Tomi K. Sawyer, David C. Dalgarno, Michael W. N. Deininger, Brian J. Druker, Tim Clackson posted to structure resistance leukemia inhibitor drug by renatomilani on 2009-11-03 02:26:41 as along with 1 person Nakamichi
	Systems biology: an evolving approach in drug discovery and development. [My Copy] Drugs in R&D, Vol. 9, No. 4. (2008), pp. 203-216. by R. L. Ho, C. A. Lieu posted to systems f1000 drug by renatomilani on 2009-11-03 00:36:06 as along with 1 person flbarroso
	F1000 Reports: Inhibitor of Apoptosis (IAP) proteins as drug targets for the treatment of cancer [My Copy] posted to inhibitor f1000 drug cancer apoptosis by renatomilani on 2009-11-03 00:33:47 as
	Modulation of Multidrug Resistance Protein 1 (MRP1/ABCC1)-Mediated Multidrug Resistance by Bivalent Apigenin Homodimers and Their Derivatives [My Copy] Journal of Medicinal Chemistry, Vol. 52, No. 17. (10 September 2009), pp. 5311-5322. by Iris L. K. Wong, Kin-Fai Chan, Ka H. Tsang, et al.Chi Y. Lam, Yunzhe Zhao, Tak H. Chan, Larry M. Chow posted to resistance p-gp drug cancer by renatomilani on 2009-09-10 23:18:51 as
	Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure [My Copy] Journal of Experimental & Clinical Cancer Research, Vol. 28, No. 1. (2009), 92. by Gustav Nilsonne, Eric Olm, Adam Szulkin, et al.Filip Mundt, Agnes Stein, Branka Kocic, Anna K. Rundlof, Aristi Fernandes, Mikael Bjornstedt, Katalin Dobra posted to signaling mesothelioma drug chemotherapy apoptosis by renatomilani on 2009-09-10 19:37:22 as
	Bio-IT World - Predicting Tumor Response to Chemotherapy [My Copy] posted to systems signaling p53 drug chemotherapy chemoresistance cancer biotech by renatomilani on 2009-08-11 20:27:02 as
	Anticancer drugs: microRNA suppresses liver cancer [My Copy] posted to cancer drug rnai by renatomilani on 2009-08-07 17:02:23 as
	Novel anticancer targets: revisiting ERBB2 and discovering ERBB3 [My Copy] Nat Rev Cancer, Vol. 9, No. 7. (18 July 2009), pp. 463-475. by Jose Baselga, Sandra M. Swain posted to cancer drug egfr review by renatomilani on 2009-07-03 17:48:44 as along with 2 people misonneh sschurer
	ERK2, but Not ERK1, Mediates Acquired and “<italic>De novo</italic>” Resistance to Imatinib Mesylate: Implication for CML Therapy [My Copy] PLoS ONE, Vol. 4, No. 7. (1 July 2009), e6124. by Clara I. Aceves-Luquero, Anupriya Agarwal, Juan L. Callejas-Valera, et al.Laura Arias-González, Azucena Esparís-Ogando, Del, Itxaso Bellón-Echeverria, Miguel A. de La cruz-Morcillo, Eva M. Galán Moya, Inmaculada M. Gimeno, Juan C. Gómez, Michael W. Deininger, Atanasio Pandiella, Ricardo S. Prieto posted to drug erk leukemia mapk resistance by renatomilani on 2009-07-01 21:26:01 as
	P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients [My Copy] BMC Cancer, Vol. 9 (23 June 2009), 199. by Ruoping Tang, Simy Cohen, Jean-Yves Perrot, et al.Anne-Marie Faussat, Claudia Zuany-Amorim, Zora Marjanovic, Hamid Morjani, Fanny Fava, Elise Corre, Ollivier Legrand, Jean-Pierre Marie posted to drug leukemia p-gp resistance by renatomilani on 2009-06-25 14:13:45 as
	Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs [My Copy] Proceedings of the National Academy of Sciences (5 June 2009) by Tsukasa Shibue, Robert A. Weinberg posted to cancer drug fak inhibitor integrin metastasis scibx signaling by renatomilani on 2009-06-15 21:46:08 as
	Viral Resistance Evolution Fully Escapes a Rationally Designed Lethal Inhibitor [My Copy] Mol Biol Evol, Vol. 26, No. 9. (1 September 2009), pp. 2041-2046. by Thomas E. Keller, Ian J. Molineux, James J. Bull posted to drug evolution inhibitor virus by renatomilani on 2009-06-09 12:10:17 as along with 1 person zwang
	The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase [My Copy] Biochemistry, Vol. 0, No. 0. (0000) by Peng Xie, Craig Streu, Jie Qin, et al.Howard Bregman, Nicholas Pagano, Eric Meggers, Ronen Marmorstein posted to cancer drug inhibitor kinase structure by renatomilani on 2009-06-09 02:11:36 as
	Chronic myelogenous leukaemia market [My Copy] Nature Reviews Drug Discovery, Vol. 8, No. 6. (08 May 2009), pp. 447-448. by Shane Storey posted to drug leukemia review by renatomilani on 2009-06-09 02:10:57 as
	A simple analogue of tumor-promoting aplysiatoxin is an antineoplastic agent rather than a tumor promoter: development of a synthetically accessible protein kinase C activator with bryostatin-like activity. [My Copy] Journal of the American Chemical Society, Vol. 131, No. 22. (10 June 2009), pp. 7573-7579. by Y. Nakagawa, R. C. Yanagita, N. Hamada, et al.A. Murakami, H. Takahashi, N. Saito, H. Nagai, K. Irie posted to cancer drug pkc by renatomilani on 2009-06-06 03:32:47 as
	Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells. [My Copy] Journal of medicinal chemistry, Vol. 52, No. 10. (28 May 2009), pp. 3191-3204. by M. D. Hall, N. K. Salam, J. L. Hellawell, et al.H. M. Fales, C. B. Kensler, J. A. Ludwig, G. Szakács, D. E. Hibbs, M. M. Gottesman posted to drug p-gp resistance by renatomilani on 2009-05-29 13:09:19 as
	Polo-like kinase 1 is overexpressed in acute myeloid leukemia and its inhibition preferentially targets the proliferation of leukemic cells [My Copy] Blood, Vol. 114, No. 3. (16 July 2009), pp. 659-662. by Annelies G. Renner, Cedric Dos Santos, Christian Recher, et al.Christian Bailly, Laurent Creancier, Anna Kruczynski, Bernard Payrastre, Stephane Manenti posted to cell-cycle drug leukemia polo by renatomilani on 2009-05-25 16:13:40 as
	Faculty of 1000 Biology \| Charting the molecular network of the drug target Bcr-Abl. [My Copy] posted to drug f1000 leukemia network by renatomilani on 2009-05-14 23:48:20 as
	Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases [My Copy] Blood (5 May 2009), blood-2009-02-200543. by Yibing Xu, Jianwu Li, Gregory D. Ferguson, et al.Frank Mercurio, Gody Khambatta, Lisa Morrison, Antonia Lopez-Girona, Laura G. Corral, David R. Webb, Brydon L. Bennett, Weilin Xie posted to cytoskeleton drug immunology rho by renatomilani on 2009-05-11 04:46:22 as
	A new screening assay for allosteric inhibitors of cSrc. [My Copy] Nature chemical biology (26 April 2009) by Jeffrey R R. Simard, Sabine Klüter, Christian Grütter, et al.Matthäus Getlik, Matthias Rabiller, Haridas B B. Rode, Daniel Rauh posted to drug inhibitor screening src by renatomilani on 2009-05-01 23:11:41 as along with 2 people justincisar paulschlesinger
	Vandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport function. [My Copy] PLoS ONE, Vol. 4, No. 4. (2009) by L. S. Zheng, F. Wang, Y. H. Li, et al.X. Zhang, L. M. Chen, Y. J. Liang, C. L. Dai, Y. Y. Yan, L. Y. Tao, Y. J. Mi, A. K. Yang, K. K. To, L. W. Fu posted to drug inhibitor p-gp by renatomilani on 2009-04-29 20:20:05 as along with 1 person and 1 group HEIRS HEIRS - Environmental Illness Research
	Small Molecules Efficiently Direct Endodermal Differentiation of Mouse and Human Embryonic Stem Cells [My Copy] Vol. 4, No. 4. (3 April 2009), pp. 348-358. by Malgorzata Borowiak, René Maehr, Shuibing Chen, et al.Alice E. Chen, Weiping Tang, Julia L. Fox, Stuart L. Schreiber, Douglas A. Melton posted to drug stem-cell tgf-beta by renatomilani on 2009-04-28 14:42:32 as
	Focus Issue: demystifying mTOR signaling. [My Copy] Science signaling, Vol. 2, No. 67. (21 April 2009), eg5. by Nancy R. Gough posted to drug egfr mtor signaling by renatomilani on 2009-04-23 19:20:33 as along with 2 people guhjy reyez
	Jak2 inhibition deactivates Lyn kinase through the SETPP2ASHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients [My Copy] Oncogene, Vol. aop, No. current. by A. K. Samanta, S. N. Chakraborty, Y. Wang, et al.H. Kantarjian, X. Sun, J. Hood, D. Perrotti, R. B. Arlinghaus posted to apoptosis cancer drug jak-stat kinase leukemia resistance signaling by renatomilani on 2009-04-14 20:00:49 as
	Drug discovery: Fresh target for cancer therapy [My Copy] Nature, Vol. 458, No. 7239. (08 April 2009), pp. 709-710. by Raymond J. Deshaies posted to drug ubiquitin by renatomilani on 2009-04-13 20:56:58 as along with 1 person reyez
	An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. [My Copy] Nature, Vol. 458, No. 7239. (9 April 2009), pp. 732-736. by Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen, et al.Allison J. Berger, James M. Gavin, Sharmila Adhikari, James E. Brownell, Kristine E. Burke, David P. Cardin, Stephen Critchley, Courtney A. Cullis, Amanda Doucette, James J. Garnsey, Jeffrey L. Gaulin, Rachel E. Gershman, Anna R. Lublinsky, Alice McDonald, Hirotake Mizutani, Usha Narayanan, Edward J. Olhava, Stephane Peluso, Mansoureh Rezaei, Michael D. Sintchak, Tina Talreja, Michael P. Thomas, Tary Traore, Stepan Vyskocil, Gabriel S. Weatherhead, Jie Yu, Julie Zhang, Lawrence R. Dick, Christopher F. Claiborne, Mark Rolfe, Joseph B. Bolen, Steven P. Langston posted to cancer drug ubiquitin by renatomilani on 2009-04-13 20:43:47 as along with 3 people guhjy absterga jbhiatt
	Local and global modes of drug action in biochemical networks [My Copy] BMC Chemical Biology, Vol. 9 (07 April 2009), 4. by Jean-Marc Schwartz, Jose C. Nacher posted to drug network by renatomilani on 2009-04-08 21:46:22 as along with 1 person schwartzjmc
	Faculty of 1000 Biology \| Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. [My Copy] posted to drug f1000 p-gp resistance structure by renatomilani on 2009-03-31 15:26:21 as
	Antiproliferative effect of ascorbic acid is associated with the inhibition of genes necessary to cell cycle progression. [My Copy] PLoS ONE, Vol. 4, No. 2. (2009) by S. Belin, F. Kaya, G. Duisit, S. Giacometti, J. Ciccolini, M. Fontés posted to cancer cell-cycle drug vitamin by renatomilani on 2009-03-30 17:45:59 as
	F1000: Antiproliferative effect of ascorbic acid is associated with the inhibition of genes necessary to cell cycle progression. [My Copy] posted to cancer cell-cycle drug f1000 vitamin by renatomilani on 2009-03-30 17:45:30 as
	BIOCHEMISTRY: Through a Mirror, Differently [My Copy] Science, Vol. 323, No. 5922. (27 March 2009), pp. 1679-1680. by Jonathan A. Sheps posted to drug p-gp structure by renatomilani on 2009-03-30 02:28:14 as
	Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. [My Copy] Science (New York, N.Y.), Vol. 323, No. 5922. (27 March 2009), pp. 1718-1722. by Stephen G. Aller, Jodie Yu, Andrew Ward, et al.Yue Weng, Srinivas Chittaboina, Rupeng Zhuo, Patina M. Harrell, Yenphuong T. Trinh, Qinghai Zhang, Ina L. Urbatsch, Geoffrey Chang posted to drug p-gp resistance structure by renatomilani on 2009-03-30 02:18:15 as along with 3 people and 1 group Copper_Calcio martainn TonyIvetac McCammon
	Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo [My Copy] BMC Systems Biology, Vol. 3, No. 1. (2009), 31. by Jesse Smith, Renee Kenney, David Gagne, et al.Brian Frushour, William Ladd, Heidi Galonek, Kristine Israelian, Jeffrey Song, Giedre Razvadauskaite, Amy Lynch, David Carney, Robin Johnson, Siva Lavu, Andre Iffland, Peter Elliott, Philip Lambert, Keith Elliston, Michael Jirousek, Jill Milne, Olivier Boss posted to age drug pathway signaling sirtuin by renatomilani on 2009-03-16 20:01:58 as along with 4 people smichan mkotlyar guhjy greg
	PKCbeta is essential for the development of CLL in the TCL1 transgenic mouse model: Validation of PKCbeta as a therapeutic target in CLL. [My Copy] Blood (23 January 2009) by Claudia Holler, Josefina D D. Pinon, Ursula Denk, et al.Christoph Heyder, Sebastian Hofbauer, Richard Greil, Alexander Egle posted to drug kinase leukemia pkc signaling by renatomilani on 2009-03-13 19:58:11 as
	Protein kinases--the major drug targets of the twenty-first century? [My Copy] Nat Rev Drug Discov, Vol. 1, No. 4. (April 2002), pp. 309-315. by P. Cohen posted to drug kinase review by renatomilani on 2009-03-10 12:21:17 as along with 1 person aqeel
	A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemia [My Copy] Proceedings of the National Academy of Sciences, Vol. 106, No. 9. (3 March 2009), pp. 3378-3383. by Qun-Ye Zhang, Jian-Hua Mao, Ping Liu, et al.Qiu-Hua Huang, Jing Lu, Yin-Yin Xie, Lin Weng, Yan Zhang, Quan Chen, Sai-Juan Chen, Zhu Chen posted to cancer drug leukemia systems by renatomilani on 2009-03-04 19:52:21 as along with 1 person Schmidtc
	Anticancer drugs: Inhibiting hedgehog [My Copy] Nature Reviews Drug Discovery, Vol. 8, No. 3. (20 February 2009), pp. 195-195. by Bethan Hughes posted to cancer drug hedgehog inhibitor by renatomilani on 2009-02-27 19:25:10 as
	Phototoxic aptamers selectively enter and kill epithelial cancer cells [My Copy] Nucl. Acids Res., Vol. 37, No. 3. (1 February 2009), pp. 866-876. by Catia S. Ferreira, Melissa C. Cheung, Sotiris Missailidis, Stuart Bisland, Jean Gariepy posted to biotech cancer dna drug by renatomilani on 2009-02-25 03:53:05 as
	The effect of the dual Src/Abl kinase inhibitor AZD0530 on Philadelphia positive leukaemia cell lines [My Copy] BMC Cancer, Vol. 9 (13 February 2009), 53. by Patricia, Oliver G. Ottmann posted to drug inhibitor leukemia methods src by renatomilani on 2009-02-19 19:08:10 as
	High-throughput screening review [My Copy] posted to biotech drug high-throughput screening statistics by renatomilani on 2009-02-19 01:35:49 as
	Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect [My Copy] Oncogene, Vol. aop, No. current. by E. Lara, A. Mai, V. Calvanese, et al.L. Altucci, P. Lopez-Nieva, M. L. Martinez-Chantar, M. Varela-Rey, D. Rotili, A. Nebbioso, S. Ropero, G. Montoya, J. Oyarzabal, S. Velasco, M. Serrano, M. Witt, A. Villar-Garea, A. Inhof, J. M. Mato, M. Esteller, M. F. Fraga posted to age apoptosis cancer drug sirtuin by renatomilani on 2009-02-13 18:17:31 as along with 1 person ajaymalik
	Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. [My Copy] posted to cancer drug regeneration screening signaling wnt by renatomilani on 2009-02-12 02:58:40 as
	A small molecule that binds Hedgehog and blocks its signaling in human cells. [My Copy] Nature chemical biology (18 January 2009) by Benjamin Z Z. Stanton, Lee F F. Peng, Nicole Maloof, et al.Kazuo Nakai, Xiang Wang, Jay L L. Duffner, Kennedy M M. Taveras, Joel M M. Hyman, Sam W W. Lee, Angela N N. Koehler, James K K. Chen, Julia L L. Fox, Anna Mandinova, Stuart L L. Schreiber posted to drug hedgehog inhibitor signaling by renatomilani on 2009-02-05 18:29:10 as
	Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. [My Copy] PLoS ONE, Vol. 4, No. 1. (2009) by S. Tiziani, A. Lodi, F. L. Khanim, M. R. Viant, C. M. Bunce, U. L. Günther posted to drug leukemia metabolomics profiling by renatomilani on 2009-02-03 19:46:37 as
	Novel Wnt antagonists target porcupine and Axin [My Copy] Nat Chem Biol, Vol. 5, No. 2. (February 2009), pp. 74-75. by Jing-Ruey J. Yeh, Randall T. Peterson posted to drug wnt by renatomilani on 2009-02-03 00:25:13 as
	SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK [My Copy] Blood, Vol. 113, No. 4. (22 January 2009), pp. 846-855. by Yutaka Okawa, Teru Hideshima, Paul Steed, et al.Sonia Vallet, Steven Hall, Ken Huang, John Rice, Amy Barabasz, Brianna Foley, Hiroshi Ikeda, Noopur Raje, Tanyel Kiziltepe, Hiroshi Yasui, Sotaro Enatsu, Kenneth C. Anderson posted to akt cancer drug erk leukemia by renatomilani on 2009-02-03 00:21:46 as
	KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients. [My Copy] Proceedings of the National Academy of Sciences of the United States of America (21 January 2009) by Ketan S S. Gajiwala, Joe C C. Wu, James Christensen, et al.Gayatri D D. Deshmukh, Wade Diehl, Jonathan P P. Dinitto, Jessie M M. English, Michael J J. Greig, You-Ai A. He, Suzanne L L. Jacques, Elizabeth A A. Lunney, Michele McTigue, David Molina, Terri Quenzer, Peter A A. Wells, Xiu Yu, Yan Zhang, Aihua Zou, Mark R R. Emmett, Alan G G. Marshall, Hui-Min M. Zhang, George D D. Demetri posted to cancer drug kinase mutation receptor resistance by renatomilani on 2009-02-02 23:43:42 as
	Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB [My Copy] Science, Vol. 323, No. 5912. (16 January 2009), pp. 396-401. by Maria A. Schumacher, Kevin M. Piro, Weijun Xu, Sonja Hansen, Kim Lewis, Richard G. Brennan posted to drug kinase resistance by renatomilani on 2009-01-27 17:54:59 as along with 1 person shuzhens

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cancer	227
kinase	213
bioinformatics	189
signaling	170
pathway	154
review	120
network	119
tool	109
microarray	99
methods	96
protein	95
evolution	78
interaction	67
gene	58
drug	58
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leukemia	57
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kinome	43
f1000	43
stem-cell	41
metabolism	41
osteogenesis	41
inhibitor	41
systems	40
bone	40
proteome	39
database	36
apoptosis	35
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statistics	34
age	31
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mapk	29
metascience	28
data	27
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sequence	24
akt	23
erk	23
cell	22
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metastasis	21
src	20
wnt	20
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resistance	19
malaria	17
development	17
tgf-beta	16
chip	16
function	16
ptp	16
p-gp	16
screening	16
modelling	15
tyrosine	15
module	15
rnai	15
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hedgehog	15
fak	14
pepchip	14
p53	14
jnk	14
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r	13
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sam	12
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ros	9
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go	6
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3d	1
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channel	1
ode	1
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cilia	1
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string	1
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engineering	1
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market	1
pain	1
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stat	1
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index	1
magic	1
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atpadp	1
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microsatellite	1
atp	1
lymphocyte	1
recombination	1
mcmc	1
chemotaxis	1
foxo	1
programming	1

renatomilani's drug [58 articles] Export

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