renatomilani's inhibitor [41 articles] Export

Recent papers added to renatomilani's library classified by the tag inhibitor. You can also see everyone's inhibitor.

	Direct inhibition of the NOTCH transcription factor complex [My Copy] Nature, Vol. 462, No. 7270. (12 November 2009), pp. 182-188. by Raymond E. Moellering, Melanie Cornejo, Tina N. Davis, et al.Cristina D. Bianco, Jon C. Aster, Stephen C. Blacklow, Andrew L. Kung, D. Gary Gilliland, Gregory L. Verdine, James E. Bradner posted to transcription-factor structure pathway notch leukemia inhibitor by renatomilani on 2009-11-16 18:58:48 as along with 4 people higueruelo gbloeb qshao cchand
	Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure - does the BCR-ABL mutation status really matter? [My Copy] Blood (30 October 2009), blood-2009-08-215939. by Susan Branford, Junia V. Melo, Timothy P. Hughes posted to leukemia inhibitor abl by renatomilani on 2009-11-06 02:02:06 as along with 1 person LeslieMudd
	AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance [My Copy] Vol. 16, No. 5. (6 November 2009), pp. 401-412. by Thomas O'Hare, William C. Shakespeare, Xiaotian Zhu, et al.Christopher A. Eide, Victor M. Rivera, Frank Wang, Lauren T. Adrian, Tianjun Zhou, Wei-Sheng Huang, Qihong Xu, Chester A. Metcalf, Jeffrey W. Tyner, Marc M. Loriaux, Amie S. Corbin, Scott Wardwell, Yaoyu Ning, Jeffrey A. Keats, Yihan Wang, Raji Sundaramoorthi, Mathew Thomas, Dong Zhou, Joseph Snodgrass, Lois Commodore, Tomi K. Sawyer, David C. Dalgarno, Michael W. N. Deininger, Brian J. Druker, Tim Clackson posted to structure resistance leukemia inhibitor drug by renatomilani on 2009-11-03 02:26:41 as along with 1 person Nakamichi
	Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity [My Copy] Oncogene, Vol. 28, No. 43. (24 August 2009), pp. 3837-3846. by C. H. Switzer, L. A. Ridnour, R. Y. S. Cheng, et al.A. Sparatore, P. Del Soldato, T. W. Moody, M. P. Vitek, D. D. Roberts, D. A. Wink posted to pp2a inhibitor cancer akt by renatomilani on 2009-11-03 00:42:02 as
	F1000 Reports: Inhibitor of Apoptosis (IAP) proteins as drug targets for the treatment of cancer [My Copy] posted to inhibitor f1000 drug cancer apoptosis by renatomilani on 2009-11-03 00:33:47 as
	Factors underlying sensitivity of cancers to small-molecule kinase inhibitors. [My Copy] Nature reviews. Drug discovery, Vol. 8, No. 9. (24 September 2009), pp. 709-723. by Pasi A. Jänne, Nathanael Gray, Jeff Settleman posted to review kinase inhibitor cancer by renatomilani on 2009-09-04 23:27:39 as along with 3 people guhjy kokphinchooi TimRooney
	Disrupting Hedgehog May Reverse Advanced Cancer, If Only Temporarily [My Copy] Science, Vol. 325, No. 5945. (4 September 2009), 1188. by Sam Kean posted to resistance pathway inhibitor hedgehog cancer by renatomilani on 2009-09-04 01:39:25 as
	Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma [My Copy] Science (2 September 2009), 1179386. by Robert L. Yauch, Gerrit J. P. Dijkgraaf, Bruno Alicke, et al.Thomas Januario, Christina P. Ahn, Thomas Holcomb, Kanan Pujara, Jeremy Stinson, Christopher A. Callahan, Tracy Tang, J. Fernando Bazan, Zhengyan Kan, Somasekar Seshagiri, Christine L. Hann, Stephen E. Gould, Jennifer A. Low, Charles M. Rudin, Frederic J. de Sauvage posted to resistance pathway inhibitor hedgehog cancer by renatomilani on 2009-09-04 01:38:46 as along with 3 people carelcad jessopher ptrobajo
	Tyrosine Kinase Inhibitors - A Review on Pharmacology, Metabolism and Side Effects [My Copy] Current Drug Metabolism, Vol. 10, No. 5. (June 2009), pp. 470-481. by Jorg T. Hartmann, Michael Haap, Hans-Georg Kopp, Hans-Peter Lipp posted to inhibitor kinase metabolism review tyrosine by renatomilani on 2009-08-10 23:23:03 as
	Bcl-2 inhibitors: small molecules with a big impact on cancer therapy [My Copy] Cell Death Differ, Vol. 16, No. 3. (19 September 2008), pp. 360-367. by M. Vogler, D. Dinsdale, M. J. S. Dyer, G. M. Cohen posted to bcl cancer inhibitor by renatomilani on 2009-08-05 16:23:08 as along with 3 people paulschlesinger tding emiko
	Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms [My Copy] Proceedings of the National Academy of Sciences, Vol. 106, No. 28. (14 July 2009), pp. 11697-11702. by Jie Lu, John S. Kovach, Francis Johnson, et al.Jeffrey Chiang, Richard Hodes, Russell Lonser, Zhengping Zhuang posted to cancer chemoresistance chemotherapy dna-damage inhibitor phosphatase pp2a signaling by renatomilani on 2009-07-15 02:23:40 as along with 1 person carlosjavierna
	Inhibitors paradoxically prime kinases [My Copy] Nat Chem Biol, Vol. 5, No. 7. (July 2009), pp. 448-449. by Stephen V. Frye, Gary L. Johnson posted to inhibitor kinase by renatomilani on 2009-06-22 23:01:40 as
	Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs [My Copy] Proceedings of the National Academy of Sciences (5 June 2009) by Tsukasa Shibue, Robert A. Weinberg posted to cancer drug fak inhibitor integrin metastasis scibx signaling by renatomilani on 2009-06-15 21:46:08 as
	Viral Resistance Evolution Fully Escapes a Rationally Designed Lethal Inhibitor [My Copy] Mol Biol Evol, Vol. 26, No. 9. (1 September 2009), pp. 2041-2046. by Thomas E. Keller, Ian J. Molineux, James J. Bull posted to drug evolution inhibitor virus by renatomilani on 2009-06-09 12:10:17 as along with 1 person zwang
	Tyrosine kinases as targets for the treatment of rheumatoid arthritis [My Copy] Nat Rev Rheumatol, Vol. 5, No. 6. (June 2009), pp. 317-324. by D'Aura, Ricardo T. Paniagua, Tamsin M. Lindstrom, William H. Robinson posted to inflammation inhibitor kinase tyrosine by renatomilani on 2009-06-09 02:12:32 as
	The Crystal Structure of BRAF in Complex with an Organoruthenium Inhibitor Reveals a Mechanism for Inhibition of an Active Form of BRAF Kinase [My Copy] Biochemistry, Vol. 0, No. 0. (0000) by Peng Xie, Craig Streu, Jie Qin, et al.Howard Bregman, Nicholas Pagano, Eric Meggers, Ronen Marmorstein posted to cancer drug inhibitor kinase structure by renatomilani on 2009-06-09 02:11:36 as
	Inhibitor hijacking of Akt activation [My Copy] Nature Chemical Biology, Vol. 5, No. 7. (24 May 2009), pp. 484-493. by Tatsuya Okuzumi, Dorothea Fiedler, Chao Zhang, et al.Daniel C. C. Gray, Brian Aizenstein, Randy Hoffman, Kevan M. M. Shokat posted to akt cancer f1000 inhibitor by renatomilani on 2009-05-29 15:47:39 as along with 1 person guhjy
	A new screening assay for allosteric inhibitors of cSrc. [My Copy] Nature chemical biology (26 April 2009) by Jeffrey R R. Simard, Sabine Klüter, Christian Grütter, et al.Matthäus Getlik, Matthias Rabiller, Haridas B B. Rode, Daniel Rauh posted to drug inhibitor screening src by renatomilani on 2009-05-01 23:11:41 as along with 2 people justincisar paulschlesinger
	PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation [My Copy] Nat Cell Biol, Vol. 11, No. 5. (May 2009), pp. 644-651. by Judy Q. Wu, Jessie Y. Guo, Wanli Tang, et al.Chih-Sheng Yang, Christopher D. Freel, Chen Chen, Angus C. Nairn, Sally Kornbluth posted to cell-cycle inhibitor kinase by renatomilani on 2009-05-01 00:13:02 as
	Vandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport function. [My Copy] PLoS ONE, Vol. 4, No. 4. (2009) by L. S. Zheng, F. Wang, Y. H. Li, et al.X. Zhang, L. M. Chen, Y. J. Liang, C. L. Dai, Y. Y. Yan, L. Y. Tao, Y. J. Mi, A. K. Yang, K. K. To, L. W. Fu posted to drug inhibitor p-gp by renatomilani on 2009-04-29 20:20:05 as along with 1 person and 1 group HEIRS HEIRS - Environmental Illness Research
	Charting the molecular network of the drug target Bcr-Abl [My Copy] Proceedings of the National Academy of Sciences, Vol. 106, No. 18. (5 May 2009), pp. 7414-7419. by Marc Brehme, Oliver Hantschel, Jacques Colinge, et al.Ines Kaupe, Melanie Planyavsky, Thomas Köcher, Karl Mechtler, Keiryn L. Bennett, Giulio Superti-Furga posted to bioinformatics inhibitor interaction leukemia methods network protein signaling by renatomilani on 2009-04-23 19:45:18 as along with 2 people mingzhi oelemento
	This title is false [My Copy] Nature, Vol. 458, No. 7241. (23 April 2009), pp. 969-969. by Mark Isalan, Matthew Morrison posted to inhibitor metascience network philosophy signaling by renatomilani on 2009-04-23 18:41:17 as along with 3 people thomaskelder pkonings bayesian
	Selectivity and therapeutic inhibition of kinases: to be or not to be? [My Copy] Nat Immunol, Vol. 10, No. 4. (19 April 2009), pp. 356-360. by Kamran Ghoreschi, Arian Laurence, John J. O'Shea posted to immunology inhibitor kinase by renatomilani on 2009-04-22 20:07:28 as along with 1 person guhjy
	Anticancer drugs: Inhibiting hedgehog [My Copy] Nature Reviews Drug Discovery, Vol. 8, No. 3. (20 February 2009), pp. 195-195. by Bethan Hughes posted to cancer drug hedgehog inhibitor by renatomilani on 2009-02-27 19:25:10 as
	New Protein Kinase CK2 Inhibitors: Jumping out of the Catalytic Box [My Copy] by R. Prudent, C. Cochet posted to ck2 inhibitor kinase review by renatomilani on 2009-02-27 02:38:00 as
	Molecular biology of BCR-ABL1-positive chronic myeloid leukemia [My Copy] Blood (30 September 2008), blood-2008-03-144790. by Alfonso Quintas-Cardama, Jorge Cortes posted to inhibitor kinase leukemia review tyrosine by renatomilani on 2009-02-20 01:11:57 as along with 3 people lrust rajeevsat cer05
	The effect of the dual Src/Abl kinase inhibitor AZD0530 on Philadelphia positive leukaemia cell lines [My Copy] BMC Cancer, Vol. 9 (13 February 2009), 53. by Patricia, Oliver G. Ottmann posted to drug inhibitor leukemia methods src by renatomilani on 2009-02-19 19:08:10 as
	Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. [My Copy] PLoS biology, Vol. 7, No. 2. (10 February 2009), e38. by Morris E. Feldman, Beth Apsel, Aino Uotila, et al.Robbie Loewith, Zachary A. Knight, Davide Ruggero, Kevan M. Shokat posted to akt cancer enzyme inhibitor kinase mtor pi3k by renatomilani on 2009-02-12 13:33:48 as along with 1 person guhjy
	Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay. [My Copy] BMC Cancer, Vol. 9 (28 January 2009), 38. by Louise, Ian A. Cree posted to cancer inhibitor pathway by renatomilani on 2009-02-10 02:23:50 as
	Role of Sirtuin Histone Deacetylase SIRT1 in Prostate Cancer: A TARGET FOR PROSTATE CANCER MANAGEMENT VIA ITS INHIBITION? [My Copy] J. Biol. Chem., Vol. 284, No. 6. (6 February 2009), pp. 3823-3832. by Brittney Jung-Hynes, Minakshi Nihal, Weixiong Zhong, Nihal Ahmad posted to age cancer inhibitor prostate sirtuin by renatomilani on 2009-02-05 18:34:36 as
	A small molecule that binds Hedgehog and blocks its signaling in human cells. [My Copy] Nature chemical biology (18 January 2009) by Benjamin Z Z. Stanton, Lee F F. Peng, Nicole Maloof, et al.Kazuo Nakai, Xiang Wang, Jay L L. Duffner, Kennedy M M. Taveras, Joel M M. Hyman, Sam W W. Lee, Angela N N. Koehler, James K K. Chen, Julia L L. Fox, Anna Mandinova, Stuart L L. Schreiber posted to drug hedgehog inhibitor signaling by renatomilani on 2009-02-05 18:29:10 as
	Targeting cancer with small molecule kinase inhibitors. [My Copy] Nature reviews. Cancer, Vol. 9, No. 1. (01 January 2009), pp. 28-39. by Jianming Zhang, Priscilla L. Yang, Nathanael S. Gray posted to cancer inhibitor kinase review by renatomilani on 2009-01-09 12:52:08 as along with 5 people saradtc kokphinchooi TimRooney sschurer guhjy
	AKT inhibitor, GSK690693, induces growth inhibition and apoptosis in acute lymphoblastic leukemia cell lines [My Copy] Blood (8 December 2008), blood-2008-02-137737. by Dana S. Levy, Jason A. Kahana, Rakesh Kumar posted to akt apoptosis inhibitor leukemia by renatomilani on 2008-12-18 11:45:17 as
	Characteristics and outcome of chronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation after therapy with tyrosine kinase inhibitors [My Copy] Blood, Vol. 112, No. 13. (15 December 2008), pp. 4839-4842. by Elias Jabbour, Hagop M. Kantarjian, Dan Jones, et al.Neeli Reddy, Susan O'Brien, Guillermo Garcia-Manero, Jan Burger, Jorge Cortes posted to domain inhibitor kinase leukemia mutation by renatomilani on 2008-12-16 18:35:31 as
	Identification of a new JNK inhibitor targeting the JNK-JIP interaction site. [My Copy] Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, No. 43. (28 October 2008), pp. 16809-16813. by J. L. Stebbins, S. K. De, T. Machleidt, et al.B. Becattini, J. Vazquez, C. Kuntzen, L. H. Chen, J. F. Cellitti, M. Riel-Mehan, A. Emdadi, G. Solinas, M. Karin, M. Pellecchia posted to inhibitor interaction jnk protein signaling by renatomilani on 2008-12-05 01:57:46 as along with 1 person higueruelo
	Protein-protein Interactions: Getting rid of JNK [My Copy] Nat Rev Drug Discov, Vol. 7, No. 12. (December 2008), pp. 975-975. by Monica H. Flight posted to inhibitor interaction jnk protein signaling by renatomilani on 2008-12-05 01:57:18 as along with 1 person reyez
	Prediction of specificity-determining residues for small-molecule kinase inhibitors [My Copy] BMC Bioinformatics, Vol. 9, No. 1. (2008) by Daniel Caffrey, Elizabeth Lunney, Deborah Moshinsky posted to inhibitor kinase prediction specificity tool by renatomilani on 2008-11-26 10:48:07 as along with 2 people reyez neils
	Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice [My Copy] Proceedings of the National Academy of Sciences (17 November 2008) by Cédric Louvet, Gregory L. Szot, Jiena Lang, et al.Michael R. Lee, Nicolas Martinier, Gideon Bollag, Shirley Zhu, Arthur Weiss, Jeffrey A. Bluestone posted to diabetes inhibitor kinase signaling tyrosine by renatomilani on 2008-11-18 12:05:22 as along with 1 person ajaymalik
	Sorafenib inhibits activation of human peripheral blood T cells by targeting LCK phosphorylation [My Copy] Leukemia, Vol. aop, No. current. by W. Zhao, Y. H. Gu, R. Song, B. Q. Qu, Q. Xu posted to inhibitor kinase by renatomilani on 2008-06-12 01:56:42 as
	Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies [My Copy] Leukemia, Vol. aop, No. current. by A. Quintás-Cardama, W. Tong, T. Manshouri, et al.F. Vega, P. A. Lennon, J. Cools, D. G. Gilliland, F. Lee, J. Cortes, H. Kantarjian, G. Garcia-Manero posted to inhibitor kinase by renatomilani on 2008-06-12 01:55:58 as
	From the Cover: Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity [My Copy] Proceedings of the National Academy of Sciences, Vol. 105, No. 8. (26 February 2008), pp. 3041-3046. by James Tsai, John T. Lee, Weiru Wang, et al.Jiazhong Zhang, Hanna Cho, Shumeye Mamo, Ryan Bremer, Sam Gillette, Jun Kong, Nikolas K. Haass, Katrin Sproesser, Ling Li, Keiran S. Smalley, Daniel Fong, Yong-Liang Zhu, Adhirai Marimuthu, Hoa Nguyen, Billy Lam, Jennifer Liu, Ivana Cheung, Julie Rice, Yoshihisa Suzuki, Catherine Luu, Calvin Settachatgul, Rafe Shellooe, John Cantwell, Sung-Hou Kim, Joseph Schlessinger, Kam Y. Zhang, Brian L. West, Ben Powell, Gaston Habets, Chao Zhang, Prabha N. Ibrahim, Peter Hirth, Dean R. Artis, Meenhard Herlyn, Gideon Bollag posted to inhibitor kinase by renatomilani on 2008-02-26 20:41:56 as

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cancer	227
kinase	213
bioinformatics	189
signaling	170
pathway	153
review	119
network	119
tool	108
microarray	98
methods	96
protein	95
evolution	78
interaction	67
expression	58
gene	58
drug	57
leukemia	56
genome	47
kinome	43
f1000	43
stem-cell	41
inhibitor	41
metabolism	41
osteogenesis	41
systems	40
bone	40
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data	27
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jnk	14
fak	14
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foxo	1
programming	1

renatomilani's inhibitor [41 articles] Export

renatomilani's tags