The frailty of adaptive hypotheses for the origins of organismal complexity. Export

@article{citeulike:1318687, abstract = {The vast majority of biologists engaged in evolutionary studies interpret virtually every aspect of biodiversity in adaptive terms. This narrow view of evolution has become untenable in light of recent observations from genomic sequencing and population-genetic theory. Numerous aspects of genomic architecture, gene structure, and developmental pathways are difficult to explain without invoking the nonadaptive forces of genetic drift and mutation. In addition, emergent biological features such as complexity, modularity, and evolvability, all of which are current targets of considerable speculation, may be nothing more than indirect by-products of processes operating at lower levels of organization. These issues are examined in the context of the view that the origins of many aspects of biological diversity, from gene-structural embellishments to novelties at the phenotypic level, have roots in nonadaptive processes, with the population-genetic environment imposing strong directionality on the paths that are open to evolutionary exploitation.}, address = {Department of Biology, Indiana University, Bloomington, IN 47405.}, author = {Lynch, Michael}, citeulike-article-id = {1318687}, citeulike-linkout-0 = {http://dx.doi.org/10.1073/pnas.0702207104}, citeulike-linkout-1 = {http://www.pnas.org/content/104/suppl_1/8597.abstract}, citeulike-linkout-2 = {http://www.pnas.org/content/104/suppl_1/8597.full.pdf}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/17494740}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=17494740}, day = {15}, doi = {10.1073/pnas.0702207104}, issn = {0027-8424}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, keywords = {adaptation, architecture, biological, complexity, evolution, evolvability, genetic, genome, modularity, network, population, selection}, month = {May}, number = {Suppl 1}, pages = {8597--8604}, posted-at = {2009-07-01 21:48:05}, priority = {2}, title = {The frailty of adaptive hypotheses for the origins of organismal complexity.}, url = {http://dx.doi.org/10.1073/pnas.0702207104}, volume = {104 Suppl 1}, year = {2007} }

TY - JOUR ID - citeulike:1318687 L3 - citeulike-article-id:1318687 N2 - The vast majority of biologists engaged in evolutionary studies interpret virtually every aspect of biodiversity in adaptive terms. This narrow view of evolution has become untenable in light of recent observations from genomic sequencing and population-genetic theory. Numerous aspects of genomic architecture, gene structure, and developmental pathways are difficult to explain without invoking the nonadaptive forces of genetic drift and mutation. In addition, emergent biological features such as complexity, modularity, and evolvability, all of which are current targets of considerable speculation, may be nothing more than indirect by-products of processes operating at lower levels of organization. These issues are examined in the context of the view that the origins of many aspects of biological diversity, from gene-structural embellishments to novelties at the phenotypic level, have roots in nonadaptive processes, with the population-genetic environment imposing strong directionality on the paths that are open to evolutionary exploitation. IS - Suppl 1 JF - Proceedings of the National Academy of Sciences of the United States of America SN - 0027-8424 AD - Department of Biology, Indiana University, Bloomington, IN 47405. EP - 8604 TI - The frailty of adaptive hypotheses for the origins of organismal complexity. VL - 104 Suppl 1 SP - 8597 KW - adaptation KW - architecture KW - biological KW - complexity KW - evolution KW - evolvability KW - genetic KW - genome KW - modularity KW - network KW - population KW - selection AU - Lynch, Michael PY - 2007/May/15/ UR - http://dx.doi.org/10.1073/pnas.0702207104 ER -