Transposable elements and an epigenetic basis for punctuated equilibria Export

@article{citeulike:5036722, abstract = {Evolution is frequently concentrated in bursts of rapid morphological change and speciation followed by long-term stasis. We propose that this pattern of punctuated equilibria results from an evolutionary tug-of-war between host genomes and transposable elements (TEs) mediated through the epigenome. According to this hypothesis, epigenetic regulatory mechanisms (RNA interference, DNA methylation and histone modifications) maintain stasis by suppressing TE mobilization. However, physiological stress, induced by climate change or invasion of new habitats, disrupts epigenetic regulation and unleashes TEs. With their capacity to drive non-adaptive host evolution, mobilized TEs can restructure the genome and displace populations from adaptive peaks, thus providing an escape from stasis and generating genetic innovations required for rapid diversification. This ldquoepi-transposon hypothesisrdquo can not only explain macroevolutionary tempo and mode, but may also resolve other long-standing controversies, such as Wright's shifting balance theory, Mayr's peripheral isolates model, and McClintock's view of genome restructuring as an adaptive response to challenge.}, address = {Department of Biology and Program in Ecology, Evolution and Conservation Biology, University of Nevada, Reno, USA; Department of History and Philosophy of Science, University of Pittsburgh, 1017 Cathedral of Learning, Pittsburgh, USA}, author = {Zeh, David W. and Zeh, Jeanne A. and Ishida, Yoichi}, citeulike-article-id = {5036722}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/bies.200900026}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/122406535/ABSTRACT}, doi = {10.1002/bies.200900026}, journal = {BioEssays}, keywords = {elements, epigenetics, evolution, evolutionary, fitness, genome, landscape, mobile, punctuated, rate, stress, transposon}, number = {7}, pages = {715--726}, posted-at = {2009-07-01 21:42:42}, priority = {2}, title = {Transposable elements and an epigenetic basis for punctuated equilibria}, url = {http://dx.doi.org/10.1002/bies.200900026}, volume = {31}, year = {2009} }

TY - JOUR ID - citeulike:5036722 L3 - citeulike-article-id:5036722 N2 - Evolution is frequently concentrated in bursts of rapid morphological change and speciation followed by long-term stasis. We propose that this pattern of punctuated equilibria results from an evolutionary tug-of-war between host genomes and transposable elements (TEs) mediated through the epigenome. According to this hypothesis, epigenetic regulatory mechanisms (RNA interference, DNA methylation and histone modifications) maintain stasis by suppressing TE mobilization. However, physiological stress, induced by climate change or invasion of new habitats, disrupts epigenetic regulation and unleashes TEs. With their capacity to drive non-adaptive host evolution, mobilized TEs can restructure the genome and displace populations from adaptive peaks, thus providing an escape from stasis and generating genetic innovations required for rapid diversification. This ldquoepi-transposon hypothesisrdquo can not only explain macroevolutionary tempo and mode, but may also resolve other long-standing controversies, such as Wright's shifting balance theory, Mayr's peripheral isolates model, and McClintock's view of genome restructuring as an adaptive response to challenge. IS - 7 JF - BioEssays AD - Department of Biology and Program in Ecology, Evolution and Conservation Biology, University of Nevada, Reno, USA; Department of History and Philosophy of Science, University of Pittsburgh, 1017 Cathedral of Learning, Pittsburgh, USA EP - 726 TI - Transposable elements and an epigenetic basis for punctuated equilibria VL - 31 SP - 715 KW - elements KW - epigenetics KW - evolution KW - evolutionary KW - fitness KW - genome KW - landscape KW - mobile KW - punctuated KW - rate KW - stress KW - transposon AU - Zeh, David AU - Zeh, Jeanne AU - Ishida, Yoichi PY - 2009/// UR - http://dx.doi.org/10.1002/bies.200900026 ER -