Background: Forces influencing the remodelling of medical curricula have clouded the visibility of pathology teaching yet its mastery is central to the study of medicine. The shortage in the workforce available for routine clinical diagnosis, research and teaching, and increasing student numbers have driven the development of innovative teaching methods. Aims: To develop teaching methods which improved student satisfaction and engagement in their learning of pathology, and which also accommodated larger classes. Methods: An iterative development cycle adopting effective use of the web and sound instructional design pedagogies was followed. Two face-to-face formats, i.e. small group and large group, and a self-directed web-based (online) format were implemented on a cohort of 220 third year medical students. Outcomes were evaluated by analysis of a student preceptions questionnaire and of students' web footprints in the online resource. Results: Themes relating to teaching techniques,