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Antibody-Mediated Rejection Criteria – an Addition to the Banff '97 Classification of Renal Allograft Rejectionby: Lorraine C. Racusen, Robert B. Colvin, Kim Solez, Michael J. Mihatsch, Philip F. Halloran, Patricia M. Campbell, Michael J. Cecka, Jean-Pierre Cosyns, Anthony J. Demetris, Michael C. Fishbein, Agnes Fogo, Peter Furness, Ian W. Gibson, Denis Glotz, Pekka Hayry, Lawrence Hunsickern, Michael Kashgarian, Ronald Kerman, Alex J. Magil, Robert Montgomery, Kunio Morozumi, Volker Nickeleit, Parmjeet Randhawa, Heinz Regele, Daniel Seron, Surya Seshan, Stale Sund, Kiril Trpkov
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AbstractAntibody-mediated rejection (AbAR) is increasingly recognized in the renal allograft population, and successful therapeutic regimens have been developed to prevent and treat AbAR, enabling excellent outcomes even in patients highly sensitized to the donor prior to transplant. It has become critical to develop standardized criteria for the pathological diagnosis of AbAR. This article presents international consensus criteria for and classification of AbAR developed based on discussions held at the Sixth Banff Conference on Allograft Pathology in 2001. This classification represents a working formulation, to be revisited as additional data accumulate in this important area of renal transplantation.
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