Molecular shuttles: directed motion of microtubules along nanoscale kinesin tracks Export

@article{citeulike:5779386, abstract = {Nature has evolved specialized molecules, motor proteins, to actively transport molecules over long distances. Such molecule-based energy dependent transport processes would be useful in nanotechnology or material sciences, for example to facilitate local assembly or repair processes, or to mediate rapid transport of nonbiological molecules. In an effort to elucidate how to control the movement of biological motors in synthetic environments, we use highly oriented poly(tetrafluoroethylene) films functionalized with the motor protein kinesin and find that they are able to direct the motion of microtubules in straight lines along the films' orientation axes. Potential mechanisms by which guidance occurs are discussed.}, author = {Dennis, John R. and Howard, Jonathon and Vogel, Viola}, citeulike-article-id = {5779386}, citeulike-linkout-0 = {http://dx.doi.org/10.1088/0957-4484/10/3/302}, doi = {10.1088/0957-4484/10/3/302}, journal = {Nanotechnology}, keywords = {alignment, c1ref, films, kinesin, lookat, microtubules, motor, orientation, proteins, shuttles}, number = {3}, pages = {232--236}, posted-at = {2009-09-13 17:52:15}, priority = {4}, title = {Molecular shuttles: directed motion of microtubules along nanoscale kinesin tracks}, url = {http://dx.doi.org/10.1088/0957-4484/10/3/302}, volume = {10}, year = {1999} }

TY - JOUR ID - citeulike:5779386 L3 - citeulike-article-id:5779386 N2 - Nature has evolved specialized molecules, motor proteins, to actively transport molecules over long distances. Such molecule-based energy dependent transport processes would be useful in nanotechnology or material sciences, for example to facilitate local assembly or repair processes, or to mediate rapid transport of nonbiological molecules. In an effort to elucidate how to control the movement of biological motors in synthetic environments, we use highly oriented poly(tetrafluoroethylene) films functionalized with the motor protein kinesin and find that they are able to direct the motion of microtubules in straight lines along the films' orientation axes. Potential mechanisms by which guidance occurs are discussed. IS - 3 JF - Nanotechnology EP - 236 TI - Molecular shuttles: directed motion of microtubules along nanoscale kinesin tracks VL - 10 SP - 232 KW - alignment KW - c1ref KW - films KW - kinesin KW - lookat KW - microtubules KW - motor KW - orientation KW - proteins KW - shuttles AU - Dennis, John AU - Howard, Jonathon AU - Vogel, Viola PY - 1999/// UR - http://dx.doi.org/10.1088/0957-4484/10/3/302 ER -