Native and mutant nickel–iron hydrogenases: Unravelling structure and function Export

@article{citeulike:5881544, abstract = {In this review, an appraisal of the progress in understanding of the NiFe-hydrogenases catalytic mechanism is presented. The article is focussed on NiFe-hydrogenases from Desulfovibrio genus, as these are among the best-characterized H 2 -splitting enzymes. The X-ray structures, catalytic reactivity, spectroscopic properties and computer modeling data of the different forms of this class of hydrogenase are analyzed. In addition, the contribution of site-directed mutagenesis studies of Desulfovibrio fructosovorans species to structure–function relationships is reviewed.}, author = {Lacey, A. and Fernandez, V. and Rousset, M.}, citeulike-article-id = {5881544}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ccr.2005.03.009}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0010854505000846}, doi = {10.1016/j.ccr.2005.03.009}, issn = {00108545}, journal = {Coordination Chemistry Reviews}, keywords = {directed, function, hydrogenases, mutagenesis, mutation, nife, site, structure}, month = {August}, number = {15-16}, pages = {1596--1608}, posted-at = {2009-10-03 17:11:46}, priority = {2}, title = {Native and mutant nickel–iron hydrogenases: Unravelling structure and function}, url = {http://dx.doi.org/10.1016/j.ccr.2005.03.009}, volume = {249}, year = {2005} }

TY - JOUR ID - citeulike:5881544 L3 - citeulike-article-id:5881544 N2 - In this review, an appraisal of the progress in understanding of the NiFe-hydrogenases catalytic mechanism is presented. The article is focussed on NiFe-hydrogenases from Desulfovibrio genus, as these are among the best-characterized H 2 -splitting enzymes. The X-ray structures, catalytic reactivity, spectroscopic properties and computer modeling data of the different forms of this class of hydrogenase are analyzed. In addition, the contribution of site-directed mutagenesis studies of Desulfovibrio fructosovorans species to structure–function relationships is reviewed. IS - 15-16 JF - Coordination Chemistry Reviews SN - 00108545 EP - 1608 TI - Native and mutant nickel–iron hydrogenases: Unravelling structure and function VL - 249 SP - 1596 KW - directed KW - function KW - hydrogenases KW - mutagenesis KW - mutation KW - nife KW - site KW - structure AU - Lacey, A AU - Fernandez, V AU - Rousset, M PY - 2005/08// UR - http://dx.doi.org/10.1016/j.ccr.2005.03.009 ER -