Yeast evolution and comparative genomics. Export

@article{Liti2005, abstract = {Recent sequencing efforts and experiments have advanced our understanding of genome evolution in yeasts, particularly the Saccharomyces yeasts. The ancestral genome of the Saccharomyces sensu stricto complex has been subject to both whole-genome duplication, followed by massive sequence loss and divergence, and segmental duplication. In addition the subtelomeric regions are subject to further duplications and rearrangements via ectopic exchanges. Translocations and other gross chromosomal rearrangements that break down syntenic relationships occur; however, they do not appear to be a driving force of speciation. Analysis of single genomes has been fruitful for hypothesis generation such as the whole-genome duplication, but comparative genomics between close and more distant species has proven to be a powerful tool in testing these hypotheses as well as elucidating evolutionary processes acting on the genome. Future work on population genomics and experimental evolution will keep yeast at the forefront of studies in genome evolution.}, address = {Institute of Genetics, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom. gianni.liti@nottingham.ac.uk}, author = {Liti, G. and Louis, E. J.}, citeulike-article-id = {469912}, citeulike-linkout-0 = {http://dx.doi.org/10.1146/annurev.micro.59.030804.121400}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15877535}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15877535}, doi = {10.1146/annurev.micro.59.030804.121400}, issn = {0066-4227}, journal = {Annu Rev Microbiol}, keywords = {a\_exam, evolution, yeast}, pages = {135--153}, posted-at = {2006-01-18 22:28:14}, priority = {2}, title = {Yeast evolution and comparative genomics.}, url = {http://dx.doi.org/10.1146/annurev.micro.59.030804.121400}, volume = {59}, year = {2005} }

TY - JOUR ID - Liti2005 L3 - citeulike-article-id:469912 N2 - Recent sequencing efforts and experiments have advanced our understanding of genome evolution in yeasts, particularly the Saccharomyces yeasts. The ancestral genome of the Saccharomyces sensu stricto complex has been subject to both whole-genome duplication, followed by massive sequence loss and divergence, and segmental duplication. In addition the subtelomeric regions are subject to further duplications and rearrangements via ectopic exchanges. Translocations and other gross chromosomal rearrangements that break down syntenic relationships occur; however, they do not appear to be a driving force of speciation. Analysis of single genomes has been fruitful for hypothesis generation such as the whole-genome duplication, but comparative genomics between close and more distant species has proven to be a powerful tool in testing these hypotheses as well as elucidating evolutionary processes acting on the genome. Future work on population genomics and experimental evolution will keep yeast at the forefront of studies in genome evolution. JF - Annu Rev Microbiol SN - 0066-4227 AD - Institute of Genetics, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom. gianni.liti@nottingham.ac.uk EP - 153 TI - Yeast evolution and comparative genomics. VL - 59 SP - 135 KW - a_exam KW - evolution KW - yeast AU - Liti, G AU - Louis, EJ PY - 2005/// UR - http://dx.doi.org/10.1146/annurev.micro.59.030804.121400 ER -