Reply: On the value of haplotype-based genotype–phenotype analysis and on data transformation in pharmacogenetics and -genomics Export

@article{Balding2007a, abstract = {I welcome the comments of Vormfelde and Brockm\"{o}ller, which I do not view as entirely contradicting me but as going further than I had space to do in my introductory article. However, I would like to put forward several caveats on their observations. Haplotype analyses can often convey advantages over analysing one SNP at a time, particularly when, as I noted on page 787 of my Review1, there are multiple, tightly linked functional variants acting in cis.}, author = {Balding, David J.}, citeulike-article-id = {1928091}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nrg1916-c2}, citeulike-linkout-1 = {http://dx.doi.org/10.1038/nrg1916-c2}, doi = {10.1038/nrg1916-c2}, issn = {1471-0056}, journal = {Nature Reviews Genetics}, keywords = {association, haplotype-methods, update-when-final}, number = {12}, posted-at = {2007-11-20 14:27:48}, priority = {2}, publisher = {Nature Publishing Group}, title = {Reply: On the value of haplotype-based genotype–phenotype analysis and on data transformation in pharmacogenetics and -genomics}, url = {http://dx.doi.org/10.1038/nrg1916-c2}, volume = {8}, year = {2007} }

TY - JOUR ID - Balding2007a L3 - citeulike-article-id:1928091 N2 - I welcome the comments of Vormfelde and Brockmöller, which I do not view as entirely contradicting me but as going further than I had space to do in my introductory article. However, I would like to put forward several caveats on their observations. Haplotype analyses can often convey advantages over analysing one SNP at a time, particularly when, as I noted on page 787 of my Review1, there are multiple, tightly linked functional variants acting in cis. IS - 12 JF - Nature Reviews Genetics SN - 1471-0056 TI - Reply: On the value of haplotype-based genotype–phenotype analysis and on data transformation in pharmacogenetics and -genomics PB - Nature Publishing Group VL - 8 KW - association KW - haplotype-methods KW - update-when-final AU - Balding, David PY - 2007/// UR - http://dx.doi.org/10.1038/nrg1916-c2 ER -