Characterization of chromosome changes in two human prostatic carcinoma cell lines (PC-3 and DU145) using chromosome painting and comparative genomic hybridization. Export

@article{citeulike:5743521, abstract = {Using chromosome painting, a study of chromosomal abnormalities has been performed in two prostatic carcinoma cell lines, PC-3 and DU145. In PC-3, this analysis revealed a highly rearranged hypotriploid karyotype with 54 to 61 chromosomes and numerous rearrangements of chromosomes 1, 3, 5, 8, 10, and 14. At passage 73, DU145 had a hypotriploid karyotype with few rearrangements of chromosomes 1, 3, 5, 12, 13, and 20, whereas at passage 153, this cell line showed a near-tetraploid karyotype with a great number of rearrangements involving chromosomes 3, 6, 8, 10, 12, and 17. A single rearrangement was shared by the 2 cell lines, an i(5)(p10). A comparative genomic hybridization study demonstrated a noticeable amplification of bands 10q22.3-q23 and 14q22-q24 in the PC-3 cell line. No amplification signal was detected for DU145.}, author = {Bernardino, J. and Bourgeois, C. A. and Muleris, M. and Dutrillaux, A. M. and Malfoy, B. and Dutrillaux, B.}, citeulike-article-id = {5743521}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/9216719}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=9216719}, day = {15}, issn = {0165-4608}, journal = {Cancer genetics and cytogenetics}, keywords = {du145, pc3, ychromo}, month = {July}, number = {2}, pages = {123--128}, posted-at = {2009-09-08 17:15:36}, priority = {2}, title = {Characterization of chromosome changes in two human prostatic carcinoma cell lines (PC-3 and DU145) using chromosome painting and comparative genomic hybridization.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/9216719}, volume = {96}, year = {1997} }

TY - JOUR ID - citeulike:5743521 L3 - citeulike-article-id:5743521 N2 - Using chromosome painting, a study of chromosomal abnormalities has been performed in two prostatic carcinoma cell lines, PC-3 and DU145. In PC-3, this analysis revealed a highly rearranged hypotriploid karyotype with 54 to 61 chromosomes and numerous rearrangements of chromosomes 1, 3, 5, 8, 10, and 14. At passage 73, DU145 had a hypotriploid karyotype with few rearrangements of chromosomes 1, 3, 5, 12, 13, and 20, whereas at passage 153, this cell line showed a near-tetraploid karyotype with a great number of rearrangements involving chromosomes 3, 6, 8, 10, 12, and 17. A single rearrangement was shared by the 2 cell lines, an i(5)(p10). A comparative genomic hybridization study demonstrated a noticeable amplification of bands 10q22.3-q23 and 14q22-q24 in the PC-3 cell line. No amplification signal was detected for DU145. IS - 2 JF - Cancer genetics and cytogenetics SN - 0165-4608 EP - 128 TI - Characterization of chromosome changes in two human prostatic carcinoma cell lines (PC-3 and DU145) using chromosome painting and comparative genomic hybridization. VL - 96 SP - 123 KW - du145 KW - pc3 KW - ychromo AU - Bernardino, J AU - Bourgeois, CA AU - Muleris, M AU - Dutrillaux, AM AU - Malfoy, B AU - Dutrillaux, B PY - 1997/07/15/ UR - http://view.ncbi.nlm.nih.gov/pubmed/9216719 ER -