Which of the many proposed methods for ac- tive learning can we expect to yield good per- formance in learning logistic regression clas- si¯ers? In this article, we evaluate di®erent approaches to determine suitable practices. Among our contributions, we test several ex- plicit objective functions for active learning: an empirical consideration lacking in the lit- erature until this point. We develop a theo- retical framework for applying di®erent loss functions motivated by work in optimal ex- perimental design. Empirical investigations demonstrate the bene¯ts of our variance re- duction method which gives attractive classi- ¯cation accuracy and matches or beats ran- dom performance in all evaluations. Of the alternative heuristic approaches, we identify a method called margin sampling as giving promising performance with little computa- tional overhead.