High-density lipoprotein metabolism and progression of atherosclerosis: new insights from the HDL Atherosclerosis Treatment Study. Export

@article{citeulike:4115329, abstract = {PURPOSE OF REVIEW: The purpose of this review is to summarize the current understanding of the potentially antiatherogenic properties of high-density lipoprotein related to its different components. RECENT FINDINGS: Recent findings on the role of the different high-density lipoprotein subspecies in reverse cholesterol transport, inflammation, endothelial dysfunction, and low-density lipoprotein oxidation are covered. Special emphasis is put on the heterogeneity of high-density lipoprotein and functional changes related to specific high-density lipoprotein particles with the potential therapeutic alterations of high-density lipoprotein metabolism. SUMMARY: The diverse action of high-density lipoprotein observed could be explained by the heterogeneity of high-density lipoprotein particles with completely different composition and properties. The modification of specific high-density lipoprotein subpopulations to reach the maximum atheroprotective effects under various pathologic conditions bears great potential in lipid research.}, author = {Asztalos, B. F. and {}}, citeulike-article-id = {4115329}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/15218401}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=15218401}, issn = {0268-4705}, journal = {Current opinion in cardiology}, keywords = {atherosclerosis, hdl}, month = {July}, number = {4}, pages = {385--391}, posted-at = {2009-02-28 12:06:45}, priority = {2}, title = {High-density lipoprotein metabolism and progression of atherosclerosis: new insights from the HDL Atherosclerosis Treatment Study.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/15218401}, volume = {19}, year = {2004} }

TY - JOUR ID - citeulike:4115329 L3 - citeulike-article-id:4115329 N2 - PURPOSE OF REVIEW: The purpose of this review is to summarize the current understanding of the potentially antiatherogenic properties of high-density lipoprotein related to its different components. RECENT FINDINGS: Recent findings on the role of the different high-density lipoprotein subspecies in reverse cholesterol transport, inflammation, endothelial dysfunction, and low-density lipoprotein oxidation are covered. Special emphasis is put on the heterogeneity of high-density lipoprotein and functional changes related to specific high-density lipoprotein particles with the potential therapeutic alterations of high-density lipoprotein metabolism. SUMMARY: The diverse action of high-density lipoprotein observed could be explained by the heterogeneity of high-density lipoprotein particles with completely different composition and properties. The modification of specific high-density lipoprotein subpopulations to reach the maximum atheroprotective effects under various pathologic conditions bears great potential in lipid research. IS - 4 JF - Current opinion in cardiology SN - 0268-4705 EP - 391 TI - High-density lipoprotein metabolism and progression of atherosclerosis: new insights from the HDL Atherosclerosis Treatment Study. VL - 19 SP - 385 KW - atherosclerosis KW - hdl AU - Asztalos, BF PY - 2004/07// UR - http://view.ncbi.nlm.nih.gov/pubmed/15218401 ER -