Identification of viral microRNAs expressed in human sacral ganglia latently infected with herpes simplex virus 2. Export

@article{citeulike:6080616, abstract = {Deep sequencing of small RNAs isolated from human sacral ganglia latently infected with herpes simplex virus 2 (HSV-2) was used to identify HSV-2 microRNAs (miRNAs) expressed during latent infection. This effort resulted in the identification of five distinct HSV-2 miRNA species, two of which, miR-H3/miR-I and miR-4/miR-II, have been previously reported. Three novel HSV-2 miRNAs were also identified, two of which, miR-H7 and miR-H9, are derived from the latency-associated transcript (LAT) and are located antisense to the viral transcript encoding transactivator ICP0. A third novel HSV-2 miRNA, miR-H10, is encoded within the UL region of the genome, 3' to the UL15 open reading frame, and is presumably excised from a novel, latent HSV-2 transcript distinct from LAT.}, author = {Umbach, Jennifer L. and Wang, Kening and Tang, Shuang and Krause, Philip R. and Mont, Erik K. and Cohen, Jeffrey I. and Cullen, Bryan R.}, citeulike-article-id = {6080616}, citeulike-linkout-0 = {http://dx.doi.org/10.1128/JVI.01712-09}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19889786}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19889786}, day = {4}, doi = {10.1128/JVI.01712-09}, issn = {1098-5514}, journal = {Journal of virology}, keywords = {mirna, virus}, month = {November}, posted-at = {2009-11-06 12:08:33}, priority = {2}, title = {Identification of viral microRNAs expressed in human sacral ganglia latently infected with herpes simplex virus 2.}, url = {http://dx.doi.org/10.1128/JVI.01712-09}, year = {2009} }

TY - JOUR ID - citeulike:6080616 L3 - citeulike-article-id:6080616 N2 - Deep sequencing of small RNAs isolated from human sacral ganglia latently infected with herpes simplex virus 2 (HSV-2) was used to identify HSV-2 microRNAs (miRNAs) expressed during latent infection. This effort resulted in the identification of five distinct HSV-2 miRNA species, two of which, miR-H3/miR-I and miR-4/miR-II, have been previously reported. Three novel HSV-2 miRNAs were also identified, two of which, miR-H7 and miR-H9, are derived from the latency-associated transcript (LAT) and are located antisense to the viral transcript encoding transactivator ICP0. A third novel HSV-2 miRNA, miR-H10, is encoded within the UL region of the genome, 3' to the UL15 open reading frame, and is presumably excised from a novel, latent HSV-2 transcript distinct from LAT. JF - Journal of virology SN - 1098-5514 TI - Identification of viral microRNAs expressed in human sacral ganglia latently infected with herpes simplex virus 2. KW - mirna KW - virus AU - Umbach, Jennifer AU - Wang, Kening AU - Tang, Shuang AU - Krause, Philip AU - Mont, Erik AU - Cohen, Jeffrey AU - Cullen, Bryan PY - 2009/11/04/ UR - http://dx.doi.org/10.1128/JVI.01712-09 ER -