Nanophotonics and Single Molecules

@incollection{citeulike:2823548, abstract = {Single emitting molecules are currently providing a new window into nanoscale systems ranging from biology to materials science. The amount of information that can be extracted from each single molecule depends upon the specific photophysical properties of the fluorophore and how these properties are affected by the nearby environment. For this reason, it is necessary to develop single-molecule emitters with as many different reporter functions as possible. The first part of this chapter describes a relatively new class of single-molecule fluorophores which offer tunable photophysical properties and, in turn, improved local reporting functionality on the nanometer length scale. The second part of this chapter presents metallic nanostructures which can address a second issue: the mismatch between the typical size of a single fluorophore (\~{}1 nm along a long dimension) and the wavelength of light (\~{}500 nm). Such nanostructures could lead to more efficient excitation of single molecules, in particular, higher excitation probability as well as reduced backgrounds, and effectively higher spatial resolution. Metallic nanostructures based on two triangles formed into a bowtie shape feature large enhancements of the local electromagnetic field and give rise to strong surface-enhanced Raman scattering of molecules. In future work, enhanced electromagnetic structures can be combined with single-molecule reporters in a variety of applications.}, author = {Moerner, W. E. and Schuck, James P. and Fromm, David P. and Kinkhabwala, Anika and Lord, Samuel J. and Nishimura, Stefanie Y. and Willets, Katherine A. and Sundaramurthy, Arvind and Kino, Gordon and He, Meng and Lu, Zhikuan and Twieg, Robert J. }, booktitle = {Nanophotonics and Single Molecules}, citeulike-article-id = {2823548}, doi = {http://dx.doi.org/10.1007/978-3-540-73924-1\_1}, editor = {Rigler, R. and Vogel, H. }, journal = {Single Molecules and Nanotechnology}, keywords = {dcdhf, reference}, pages = {1--23}, posted-at = {2008-05-22 19:22:21}, priority = {0}, title = {Nanophotonics and Single Molecules}, url = {http://dx.doi.org/10.1007/978-3-540-73924-1\_1}, year = {2008} }

TY - CHAP ID - citeulike:2823548 L3 - citeulike-article-id:2823548 TI - Nanophotonics and Single Molecules T2 - Nanophotonics and Single Molecules JF - Single Molecules and Nanotechnology SP - 1 EP - 23 N2 - Single emitting molecules are currently providing a new window into nanoscale systems ranging from biology to materials science. The amount of information that can be extracted from each single molecule depends upon the specific photophysical properties of the fluorophore and how these properties are affected by the nearby environment. For this reason, it is necessary to develop single-molecule emitters with as many different reporter functions as possible. The first part of this chapter describes a relatively new class of single-molecule fluorophores which offer tunable photophysical properties and, in turn, improved local reporting functionality on the nanometer length scale. The second part of this chapter presents metallic nanostructures which can address a second issue: the mismatch between the typical size of a single fluorophore (~1 nm along a long dimension) and the wavelength of light (~500 nm). Such nanostructures could lead to more efficient excitation of single molecules, in particular, higher excitation probability as well as reduced backgrounds, and effectively higher spatial resolution. Metallic nanostructures based on two triangles formed into a bowtie shape feature large enhancements of the local electromagnetic field and give rise to strong surface-enhanced Raman scattering of molecules. In future work, enhanced electromagnetic structures can be combined with single-molecule reporters in a variety of applications. KW - dcdhf KW - reference AU - Moerner, WE AU - Schuck, James AU - Fromm, David AU - Kinkhabwala, Anika AU - Lord, Samuel AU - Nishimura, Stefanie AU - Willets, Katherine AU - Sundaramurthy, Arvind AU - Kino, Gordon AU - He, Meng AU - Lu, Zhikuan AU - Twieg, Robert A2 - Rigler, R A2 - Vogel, H PY - 2008/// UR - http://dx.doi.org/10.1007/978-3-540-73924-1_1 ER -