Radioactivity-Synchronized Fluorescence Enhancement Using a Radionuclide Fluorescence-Quenched Dye Export

@article{citeulike:4808702, abstract = {PMID: 19514722 We demonstrate the first evidence of radioactivity-synchronized fluorescence quenching of a near-infrared light-emitting dye by a radionuclide, 64Cu, and subsequent fluorescence enhancement upon 64Cu decay to the daughter isotopes 64Ni and 64Zn. The dynamic switch from high radioactivity and low fluorescence to low radioactivity and high fluorescence is potentially useful for developing complementary multimodal imaging and detection platforms for chemical, environmental, and biomedical applications as well as for unraveling the mechanisms of metal-induced dynamic fluorescence changes.}, author = {Berezin, Mikhail Y. and Guo, Kevin and Teng, Bao and Edwards, W. Barry and Anderson, Carolyn J. and Vasalatiy, Olga and Gandjbakhche, Amir and Griffiths, Gary L. and Achilefu, Samuel}, citeulike-article-id = {4808702}, citeulike-linkout-0 = {http://dx.doi.org/10.1021/ja903685b}, citeulike-linkout-1 = {http://pubs.acs.org/doi/abs/10.1021/ja903685b}, doi = {10.1021/ja903685b}, journal = {Journal of the American Chemical Society}, keywords = {fluorogenic, readout}, month = {July}, number = {26}, pages = {9198--9200}, posted-at = {2009-06-11 07:50:25}, priority = {2}, title = {Radioactivity-Synchronized Fluorescence Enhancement Using a Radionuclide Fluorescence-Quenched Dye}, url = {http://dx.doi.org/10.1021/ja903685b}, volume = {131}, year = {2009} }

TY - JOUR ID - citeulike:4808702 L3 - citeulike-article-id:4808702 N2 - PMID: 19514722 We demonstrate the first evidence of radioactivity-synchronized fluorescence quenching of a near-infrared light-emitting dye by a radionuclide, 64Cu, and subsequent fluorescence enhancement upon 64Cu decay to the daughter isotopes 64Ni and 64Zn. The dynamic switch from high radioactivity and low fluorescence to low radioactivity and high fluorescence is potentially useful for developing complementary multimodal imaging and detection platforms for chemical, environmental, and biomedical applications as well as for unraveling the mechanisms of metal-induced dynamic fluorescence changes. IS - 26 JF - Journal of the American Chemical Society EP - 9200 TI - Radioactivity-Synchronized Fluorescence Enhancement Using a Radionuclide Fluorescence-Quenched Dye VL - 131 SP - 9198 KW - fluorogenic KW - readout AU - Berezin, Mikhail AU - Guo, Kevin AU - Teng, Bao AU - Edwards, Barry AU - Anderson, Carolyn AU - Vasalatiy, Olga AU - Gandjbakhche, Amir AU - Griffiths, Gary AU - Achilefu, Samuel PY - 2009/07/08/ UR - http://dx.doi.org/10.1021/ja903685b ER -