Biomimetic supported membranes from amphiphilic block copolymers Export

@article{citeulike:6071060, abstract = {A unique combination of surface chemistry and self-assembly of amphiphilic block copolymers was employed to obtain-for the first time-solid-supported biomimetic polymer bilayers. An organized monolayer from sulfur-functionalized poly(butadiene)-b-poly(ethylene oxide) was covalently attached to ultrasmooth gold upon Langmuir-Blodgett transfer. Hydrophobic interactions, on the other hand, were exploited to attach the second monolayer. As a result, we obtained a homogeneous hydrophilic-hydrophobic-hydrophilic structure, similar to supported lipid bilayers by architecture, stability and fluidity. Our polymer bilayers, however, outperform such lipid membranes with regard to tunability of thickness and stability in gaseous environments.As characterized by surface analysis tools (AFM, SPR), solid-supported polymer membranes are smooth with a thickness of ca. 11 nm, resistant to rinsing with aqueous solutions and stable upon drying and rehydration. These properties could be attractive for nanotechnological applications, such as immobilization of functional molecules or nanoparticles, sensor development or preparation of chemically responsive functional surfaces.}, author = {Belegrinou, Serena and Dorn, Jan and Kreiter, Max and Kita-Tokarczyk, Katarzyna and Sinner, Eva-Kathrin and Meier, Wolfgang}, citeulike-article-id = {6071060}, citeulike-linkout-0 = {http://dx.doi.org/10.1039/b917318h}, citeulike-linkout-1 = {http://www.rsc.org/Publishing/Journals/article.asp?doi=b917318h}, doi = {10.1039/b917318h}, journal = {Soft Matter}, keywords = {biomimetic, polymers, supported-bilayer, surface}, posted-at = {2009-11-04 19:08:48}, priority = {2}, publisher = {The Royal Society of Chemistry}, title = {Biomimetic supported membranes from amphiphilic block copolymers}, url = {http://dx.doi.org/10.1039/b917318h}, year = {2010} }

TY - JOUR ID - citeulike:6071060 L3 - citeulike-article-id:6071060 N2 - A unique combination of surface chemistry and self-assembly of amphiphilic block copolymers was employed to obtain-for the first time-solid-supported biomimetic polymer bilayers. An organized monolayer from sulfur-functionalized poly(butadiene)-b-poly(ethylene oxide) was covalently attached to ultrasmooth gold upon Langmuir-Blodgett transfer. Hydrophobic interactions, on the other hand, were exploited to attach the second monolayer. As a result, we obtained a homogeneous hydrophilic-hydrophobic-hydrophilic structure, similar to supported lipid bilayers by architecture, stability and fluidity. Our polymer bilayers, however, outperform such lipid membranes with regard to tunability of thickness and stability in gaseous environments.As characterized by surface analysis tools (AFM, SPR), solid-supported polymer membranes are smooth with a thickness of ca. 11 nm, resistant to rinsing with aqueous solutions and stable upon drying and rehydration. These properties could be attractive for nanotechnological applications, such as immobilization of functional molecules or nanoparticles, sensor development or preparation of chemically responsive functional surfaces. JF - Soft Matter TI - Biomimetic supported membranes from amphiphilic block copolymers PB - The Royal Society of Chemistry KW - biomimetic KW - polymers KW - supported-bilayer KW - surface AU - Belegrinou, Serena AU - Dorn, Jan AU - Kreiter, Max AU - Kita-Tokarczyk, Katarzyna AU - Sinner, Eva-Kathrin AU - Meier, Wolfgang PY - 2010/// UR - http://dx.doi.org/10.1039/b917318h ER -