Epigenetic variation in Arabidopsis disease resistance. Export

@article{citeulike:1115466, abstract = {Plant pathogen resistance is mediated by a large repertoire of resistance (R) genes, which are often clustered in the genome and show a high degree of genetic variation. Here, we show that an Arabidopsis thaliana R-gene cluster is also subject to epigenetic variation. We describe a heritable but metastable epigenetic variant bal that overexpresses the R-like gene At4g16890 from a gene cluster on Chromosome 4. The bal variant and Arabidopsis transgenics overexpressing the At4g16890 gene are dwarfed and constitutively activate the salicylic acid (SA)-dependent defense response pathway. Overexpression of a related R-like gene also occurs in the ssi1 (suppressor of SA insensitivity 1) background, suggesting that ssi1 is mechanistically related to bal.}, address = {Department of Biology, Washington University, St. Louis, Missouri 63130, USA.}, author = {Stokes, T. L. and Kunkel, B. N. and Richards, E. J.}, citeulike-article-id = {1115466}, citeulike-linkout-0 = {http://dx.doi.org/10.1101/gad.952102}, citeulike-linkout-1 = {http://www.genesdev.org/cgi/content/abstract/16/2/171}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/11799061}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=11799061}, day = {15}, doi = {10.1101/gad.952102}, issn = {0890-9369}, journal = {Genes Dev}, keywords = {bal1, epigenetics, r, ssi1}, month = {January}, number = {2}, pages = {171--182}, posted-at = {2007-02-21 01:29:33}, priority = {2}, title = {Epigenetic variation in Arabidopsis disease resistance.}, url = {http://dx.doi.org/10.1101/gad.952102}, volume = {16}, year = {2002} }

TY - JOUR ID - citeulike:1115466 L3 - citeulike-article-id:1115466 N2 - Plant pathogen resistance is mediated by a large repertoire of resistance (R) genes, which are often clustered in the genome and show a high degree of genetic variation. Here, we show that an Arabidopsis thaliana R-gene cluster is also subject to epigenetic variation. We describe a heritable but metastable epigenetic variant bal that overexpresses the R-like gene At4g16890 from a gene cluster on Chromosome 4. The bal variant and Arabidopsis transgenics overexpressing the At4g16890 gene are dwarfed and constitutively activate the salicylic acid (SA)-dependent defense response pathway. Overexpression of a related R-like gene also occurs in the ssi1 (suppressor of SA insensitivity 1) background, suggesting that ssi1 is mechanistically related to bal. IS - 2 JF - Genes Dev SN - 0890-9369 AD - Department of Biology, Washington University, St. Louis, Missouri 63130, USA. EP - 182 TI - Epigenetic variation in Arabidopsis disease resistance. VL - 16 SP - 171 KW - bal1 KW - epigenetics KW - r KW - ssi1 AU - Stokes, TL AU - Kunkel, BN AU - Richards, EJ PY - 2002/01/15/ UR - http://dx.doi.org/10.1101/gad.952102 ER -