ARG1 (altered response to gravity) encodes a DnaJ-like protein that potentially interacts with the cytoskeleton. Export

@article{citeulike:119298, abstract = {Gravitropism allows plant organs to direct their growth at a specific angle from the gravity vector, promoting upward growth for shoots and downward growth for roots. Little is known about the mechanisms underlying gravitropic signal transduction. We found that mutations in the ARG1 locus of Arabidopsis thaliana alter root and hypocotyl gravitropism without affecting phototropism, root growth responses to phytohormones or inhibitors of auxin transport, or starch accumulation. The positional cloning of ARG1 revealed a DnaJ-like protein containing a coiled-coil region homologous to coiled coils found in cytoskeleton-interacting proteins. These data suggest that ARG1 participates in a gravity-signaling process involving the cytoskeleton. A combination of Northern blot studies and analysis of ARG1-GUS fusion-reporter expression in transgenic plants demonstrated that ARG1 is expressed in all organs. Ubiquitous ARG1 expression in Arabidopsis and the identification of an ortholog in Caenorhabditis elegans suggest that ARG1 is involved in other essential processes.}, address = {Laboratory of Genetics, University of Wisconsin-Madison, 445 Henry Mall, Madison, WI 53706, USA.}, author = {Sedbrook, J. C. and Chen, R. and Masson, P. H.}, citeulike-article-id = {119298}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/9927707}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=9927707}, day = {2}, issn = {0027-8424}, journal = {Proc Natl Acad Sci U S A}, keywords = {arg1, dnaj, gravity}, month = {February}, number = {3}, pages = {1140--1145}, posted-at = {2007-03-21 08:47:08}, priority = {2}, title = {ARG1 (altered response to gravity) encodes a DnaJ-like protein that potentially interacts with the cytoskeleton.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/9927707}, volume = {96}, year = {1999} }

TY - JOUR ID - citeulike:119298 L3 - citeulike-article-id:119298 N2 - Gravitropism allows plant organs to direct their growth at a specific angle from the gravity vector, promoting upward growth for shoots and downward growth for roots. Little is known about the mechanisms underlying gravitropic signal transduction. We found that mutations in the ARG1 locus of Arabidopsis thaliana alter root and hypocotyl gravitropism without affecting phototropism, root growth responses to phytohormones or inhibitors of auxin transport, or starch accumulation. The positional cloning of ARG1 revealed a DnaJ-like protein containing a coiled-coil region homologous to coiled coils found in cytoskeleton-interacting proteins. These data suggest that ARG1 participates in a gravity-signaling process involving the cytoskeleton. A combination of Northern blot studies and analysis of ARG1-GUS fusion-reporter expression in transgenic plants demonstrated that ARG1 is expressed in all organs. Ubiquitous ARG1 expression in Arabidopsis and the identification of an ortholog in Caenorhabditis elegans suggest that ARG1 is involved in other essential processes. IS - 3 JF - Proc Natl Acad Sci U S A SN - 0027-8424 AD - Laboratory of Genetics, University of Wisconsin-Madison, 445 Henry Mall, Madison, WI 53706, USA. EP - 1145 TI - ARG1 (altered response to gravity) encodes a DnaJ-like protein that potentially interacts with the cytoskeleton. VL - 96 SP - 1140 KW - arg1 KW - dnaj KW - gravity AU - Sedbrook, JC AU - Chen, R AU - Masson, PH PY - 1999/02/02/ UR - http://view.ncbi.nlm.nih.gov/pubmed/9927707 ER -