Plant disease susceptibility conferred by a "resistance" gene Export

@article{citeulike:1629324, abstract = {Edited by Steven P. Briggs, University of California at San Diego, La Jolla, CA, and approved July 12, 2007 (received for review March 20, 2007)The molecular nature of many plant disease resistance (R) genes is known; the largest class encodes nucleotide-binding site-leucine-rich repeat (NBS-LRR) proteins that are structurally related to proteins involved in innate immunity in animals. Few genes conferring disease susceptibility, on the other hand, have been identified. Recent identification of susceptibility to the fungus Cochliobolus victoriae in Arabidopsis thaliana has enabled our cloning of LOV1, a disease susceptibility gene that, paradoxically, is a member of the NBS-LRR resistance gene family. We found LOV1 mediates responses associated with defense, but mutations in known defense response pathways do not prevent susceptibility to C. victoriae. These findings demonstrate that NBS-LRR genes can condition disease susceptibility and resistance and may have implications for R gene deployment. 10.1073/pnas.0702572104}, author = {Lorang, Jennifer M. and Sweat, Teresa A. and Wolpert, Thomas J.}, citeulike-article-id = {1629324}, citeulike-linkout-0 = {http://dx.doi.org/10.1073/pnas.0702572104}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/17804803}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=17804803}, day = {5}, doi = {10.1073/pnas.0702572104}, journal = {Proceedings of the National Academy of Sciences}, keywords = {lov1, r}, month = {September}, pages = {0702572104+}, posted-at = {2007-09-07 03:22:42}, priority = {2}, title = {Plant disease susceptibility conferred by a "resistance" gene}, url = {http://dx.doi.org/10.1073/pnas.0702572104}, year = {2007} }

TY - JOUR ID - citeulike:1629324 L3 - citeulike-article-id:1629324 N2 - Edited by Steven P. Briggs, University of California at San Diego, La Jolla, CA, and approved July 12, 2007 (received for review March 20, 2007)The molecular nature of many plant disease resistance (R) genes is known; the largest class encodes nucleotide-binding site-leucine-rich repeat (NBS-LRR) proteins that are structurally related to proteins involved in innate immunity in animals. Few genes conferring disease susceptibility, on the other hand, have been identified. Recent identification of susceptibility to the fungus Cochliobolus victoriae in Arabidopsis thaliana has enabled our cloning of LOV1, a disease susceptibility gene that, paradoxically, is a member of the NBS-LRR resistance gene family. We found LOV1 mediates responses associated with defense, but mutations in known defense response pathways do not prevent susceptibility to C. victoriae. These findings demonstrate that NBS-LRR genes can condition disease susceptibility and resistance and may have implications for R gene deployment. 10.1073/pnas.0702572104 JF - Proceedings of the National Academy of Sciences TI - Plant disease susceptibility conferred by a "resistance" gene SP - 0702572104 KW - lov1 KW - r AU - Lorang, Jennifer AU - Sweat, Teresa AU - Wolpert, Thomas PY - 2007/09/05/ UR - http://dx.doi.org/10.1073/pnas.0702572104 ER -