Gene3D: modelling protein structure, function and evolution Export

@article{137, abstract = {The Gene3D release 4 database and web portal (http://cathwww.biochem.ucl.ac.uk:8080/Gene3D) provide a combined structural, functional and evolutionary view of the protein world. It is focussed on providing structural annotation for protein sequences without structural representatives--including the complete proteome sets of over 240 different species. The protein sequences have also been clustered into whole-chain families so as to aid functional prediction. The structural annotation is generated using HMM models based on the CATH domain families; CATH is a repository for manually deduced protein domains. Amongst the changes from the last publication are: the addition of over 100 genomes and the UniProt sequence database, domain data from Pfam, metabolic pathway and functional data from COGs, KEGG and GO, and protein-protein interaction data from MINT and BIND. The website has been rebuilt to allow more sophisticated querying and the data returned is presented in a clearer format with greater functionality. Furthermore, all data can be downloaded in a simple XML format, allowing users to carry out complex investigations at their own computers.}, annote = {1362-4962 (Electronic) Journal Article Research Support, Non-U.S. Gov't}, author = {Yeats, C. and Maibaum, M. and Marsden, R. and Dibley, M. and Lee, D. and Addou, S. and Orengo, C. A.}, citeulike-article-id = {2114368}, journal = {Nucleic Acids Res}, keywords = {bibtex-import}, month = {Jan}, number = {Database issue}, pages = {D281--4}, posted-at = {2007-12-14 15:12:24}, priority = {0}, title = {Gene3D: modelling protein structure, function and evolution}, volume = {34}, year = {2006} }

TY - JOUR ID - 137 L3 - citeulike-article-id:2114368 N2 - The Gene3D release 4 database and web portal (http://cathwww.biochem.ucl.ac.uk:8080/Gene3D) provide a combined structural, functional and evolutionary view of the protein world. It is focussed on providing structural annotation for protein sequences without structural representatives--including the complete proteome sets of over 240 different species. The protein sequences have also been clustered into whole-chain families so as to aid functional prediction. The structural annotation is generated using HMM models based on the CATH domain families; CATH is a repository for manually deduced protein domains. Amongst the changes from the last publication are: the addition of over 100 genomes and the UniProt sequence database, domain data from Pfam, metabolic pathway and functional data from COGs, KEGG and GO, and protein-protein interaction data from MINT and BIND. The website has been rebuilt to allow more sophisticated querying and the data returned is presented in a clearer format with greater functionality. Furthermore, all data can be downloaded in a simple XML format, allowing users to carry out complex investigations at their own computers. IS - Database issue JF - Nucleic Acids Res EP - 4 TI - Gene3D: modelling protein structure, function and evolution VL - 34 SP - D281 KW - bibtex-import AU - Yeats, C AU - Maibaum, M AU - Marsden, R AU - Dibley, M AU - Lee, D AU - Addou, S AU - Orengo, CA PY - 2006/Jan 1// ER -