Mechanism of ribosome assisted protein folding: a new insight into rRNA functions. Export

@article{citeulike:6093136, abstract = {The peptidyl transferase center (PTC), present in the domain V of 23S rRNA of bacteria can act as a general protein folding modulator. Any general function of a nucleic acid polymer (DNA or RNA) is always related to specific sequence/sequences. The ribosome mediated protein folding also involves a specific interaction between the nucleotides of peptidyl transferase center and the amino acids of an unfolded protein. In this article the mechanism of rRNA assisted protein folding and its significance in the light of high resolution crystal structure of ribosome are discussed.}, author = {Samanta, Dibyendu and Das, Anindita and Bhattacharya, Arpita and Basu, Arunima and Das, Debasis and DasGupta, Chanchal}, citeulike-article-id = {6093136}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.bbrc.2009.04.106}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/19401192}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=19401192}, day = {26}, doi = {10.1016/j.bbrc.2009.04.106}, issn = {1090-2104}, journal = {Biochemical and biophysical research communications}, keywords = {co-translation, folding, function, ribosome, rrna}, month = {June}, number = {2}, pages = {137--140}, posted-at = {2009-11-10 13:52:42}, priority = {2}, title = {Mechanism of ribosome assisted protein folding: a new insight into rRNA functions.}, url = {http://dx.doi.org/10.1016/j.bbrc.2009.04.106}, volume = {384}, year = {2009} }

TY - JOUR ID - citeulike:6093136 L3 - citeulike-article-id:6093136 N2 - The peptidyl transferase center (PTC), present in the domain V of 23S rRNA of bacteria can act as a general protein folding modulator. Any general function of a nucleic acid polymer (DNA or RNA) is always related to specific sequence/sequences. The ribosome mediated protein folding also involves a specific interaction between the nucleotides of peptidyl transferase center and the amino acids of an unfolded protein. In this article the mechanism of rRNA assisted protein folding and its significance in the light of high resolution crystal structure of ribosome are discussed. IS - 2 JF - Biochemical and biophysical research communications SN - 1090-2104 EP - 140 TI - Mechanism of ribosome assisted protein folding: a new insight into rRNA functions. VL - 384 SP - 137 KW - co-translation KW - folding KW - function KW - ribosome KW - rrna AU - Samanta, Dibyendu AU - Das, Anindita AU - Bhattacharya, Arpita AU - Basu, Arunima AU - Das, Debasis AU - DasGupta, Chanchal PY - 2009/06/26/ UR - http://dx.doi.org/10.1016/j.bbrc.2009.04.106 ER -