In vivo measurement of partial oxygen pressure in large vessels and in the reticuloendothelial system using fast 19F-MRI Export

@article{NO95, abstract = {Quantitative in vivo 19F-MRI was performed in a rat model to monitor partial oxygen pressure (pO2) using a perfluorocarbon (PFC) emulsion as contrast agent. On Days 1, 4, and 8 postin-jection of the PFC emulsion, transaxial T1 and pO2 maps were acquired of the abdomen of rats that were consecutively ventilated with pure oxygen, air, and a mixture of 10\% oxygen and 90\% nitrogen. The images had a resolution of 0.75 mm x 0.75 mm x 2 mm and a total acquisition time of 24 min. In these images it was possible to distinguish between different vessels and hepatic and splenic tissue in the selected imaging plane. Serial 19F-MRI measurements on the different days postinjection of the PFC allowed to determine separately the pO2 of arterial and venous blood and the intracellular pO2 in macrophages of the liver and spleen.}, address = {Physikalisches Institut, EP 5, Universit\"{a}t W\"{u}rzburg, Am Hubland, W\"{u}rzburg; Neurologische Universit\"{a}tsklinik, W\"{u}rzburg; FF-ME MUSC Institut f\"{u}r Flugmedizin, DLR, Linder H\"{o}he, K\"{o}ln; Physiologisches Institut, R\"{o}ntgenring 9, W\"{u}rzburg, Germany.}, author = {N\"{o}th, Ulrike and Morrissey, Sean P. and Deichmann, Ralf and Adolf, Holger and Schwarzbauer, Christian and Lutz, Joachim and Haase, Axel}, citeulike-article-id = {4217051}, citeulike-linkout-0 = {http://dx.doi.org/10.1002/mrm.1910340513}, citeulike-linkout-1 = {http://www3.interscience.wiley.com/cgi-bin/abstract/112151519/ABSTRACT}, doi = {10.1002/mrm.1910340513}, journal = {Magnetic Resonance in Medicine}, keywords = {19f-mri, 19fo, no95, perfluorocarbons}, number = {5}, pages = {738--745}, posted-at = {2009-03-25 09:59:11}, priority = {0}, title = {In vivo measurement of partial oxygen pressure in large vessels and in the reticuloendothelial system using fast 19F-MRI}, url = {http://dx.doi.org/10.1002/mrm.1910340513}, volume = {34}, year = {1995} }

TY - JOUR ID - NO95 L3 - citeulike-article-id:4217051 N2 - Quantitative in vivo 19F-MRI was performed in a rat model to monitor partial oxygen pressure (pO2) using a perfluorocarbon (PFC) emulsion as contrast agent. On Days 1, 4, and 8 postin-jection of the PFC emulsion, transaxial T1 and pO2 maps were acquired of the abdomen of rats that were consecutively ventilated with pure oxygen, air, and a mixture of 10% oxygen and 90% nitrogen. The images had a resolution of 0.75 mm x 0.75 mm x 2 mm and a total acquisition time of 24 min. In these images it was possible to distinguish between different vessels and hepatic and splenic tissue in the selected imaging plane. Serial 19F-MRI measurements on the different days postinjection of the PFC allowed to determine separately the pO2 of arterial and venous blood and the intracellular pO2 in macrophages of the liver and spleen. IS - 5 JF - Magnetic Resonance in Medicine AD - Physikalisches Institut, EP 5, Universität Würzburg, Am Hubland, Würzburg; Neurologische Universitätsklinik, Würzburg; FF-ME MUSC Institut für Flugmedizin, DLR, Linder Höhe, Köln; Physiologisches Institut, Röntgenring 9, Würzburg, Germany. EP - 745 TI - In vivo measurement of partial oxygen pressure in large vessels and in the reticuloendothelial system using fast 19F-MRI VL - 34 SP - 738 KW - 19f-mri KW - 19fo KW - no95 KW - perfluorocarbons AU - Nöth, Ulrike AU - Morrissey, Sean AU - Deichmann, Ralf AU - Adolf, Holger AU - Schwarzbauer, Christian AU - Lutz, Joachim AU - Haase, Axel PY - 1995/// UR - http://dx.doi.org/10.1002/mrm.1910340513 ER -