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Metagenomic diagnosis of bacterial infections.

by: Shota Nakamura, Norihiro Maeda, Ionut Mihai M. Miron, Myonsun Yoh, Kaori Izutsu, Chidoh Kataoka, Takeshi Honda, Teruo Yasunaga, Takaaki Nakaya, Jun Kawai, Yoshihide Hayashizaki, Toshihiro Horii, Tetsuya Iida
Emerging infectious diseases, Vol. 14, No. 11. (November 2008), pp. 1784-1786, doi:10.3201/eid1411.080589  Key: citeulike:10852816

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Abstract

To test the ability of high-throughput DNA sequencing to detect bacterial pathogens, we used it on DNA from a patient's feces during and after diarrheal illness. Sequences showing best matches for Campylobacter jejuni were detected only in the illness sample. Various bacteria may be detectable with this metagenomic approach.


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