Cortical rewiring and information storage Export

@article{citeulike:353538, abstract = {Current thinking about long-term memory in the cortex is focused on changes in the strengths of connections between neurons. But ongoing structural plasticity in the adult brain, including synapse formation/elimination and remodelling of axons and dendrites, suggests that memory could also depend on learning-induced changes in the cortical 'wiring diagram'. Given that the cortex is sparsely connected, wiring plasticity could provide a substantial boost in storage capacity, although at a cost of more elaborate biological machinery and slower learning.}, author = {Chklovskii, D. B. and Mel, B. W. and Svoboda, K.}, citeulike-article-id = {353538}, citeulike-linkout-0 = {http://dx.doi.org/10.1038/nature03012}, citeulike-linkout-1 = {http://adsabs.harvard.edu/cgi-bin/nph-bib_query?bibcode=2004Natur.431..782C}, citeulike-linkout-2 = {http://dx.doi.org/10.1038/nature03012}, citeulike-linkout-3 = {http://view.ncbi.nlm.nih.gov/pubmed/15483599}, citeulike-linkout-4 = {http://www.hubmed.org/display.cgi?uids=15483599}, day = {14}, doi = {10.1038/nature03012}, journal = {Nature}, keywords = {capacity, dendrites, learning, plasticity, spines}, month = {October}, number = {7010}, pages = {782--788}, posted-at = {2006-11-23 16:36:33}, priority = {2}, title = {Cortical rewiring and information storage}, url = {http://dx.doi.org/10.1038/nature03012}, volume = {431}, year = {2004} }

TY - JOUR ID - citeulike:353538 L3 - citeulike-article-id:353538 N2 - Current thinking about long-term memory in the cortex is focused on changes in the strengths of connections between neurons. But ongoing structural plasticity in the adult brain, including synapse formation/elimination and remodelling of axons and dendrites, suggests that memory could also depend on learning-induced changes in the cortical 'wiring diagram'. Given that the cortex is sparsely connected, wiring plasticity could provide a substantial boost in storage capacity, although at a cost of more elaborate biological machinery and slower learning. IS - 7010 JF - Nature EP - 788 TI - Cortical rewiring and information storage VL - 431 SP - 782 KW - capacity KW - dendrites KW - learning KW - plasticity KW - spines AU - Chklovskii, DB AU - Mel, BW AU - Svoboda, K PY - 2004/10/14/ UR - http://dx.doi.org/10.1038/nature03012 ER -