An oxidative stress score as a combined measure of the pro-oxidant and anti-oxidant counterparts in patients with coronary artery disease Export

@article{citeulike:3441140, abstract = {Oxidative stress plays a key role in the pathogenesis and development of atherosclerosis. To evaluate the relationship between a novel oxidative stress index (reflecting both oxidative and anti-oxidant counterparts) with traditional cardiovascular risk factors and C-reactive protein (CRP) in coronary artery disease (CAD). 100 angiographically proven CAD and 70 control subjects (mean age: 65\ \&\#xb1;\ 10\&\#xa0;years, 110 males), underwent a global cardiovascular risk assessment and serum CRP and oxidative stress estimation. The Oxidative-INDEX was calculated after automated evaluation of serum hydroperoxides and total anti-oxidant capacity (D-ROM and OXY-adsorbent Test, Diacron, Italy) subtracting the OXY standardized variable from the ROM standardized variable. Oxidative stress represents a shared molecular pathway in atherosclerotic-related conditions, and its estimation by the automated Oxidative-INDEX could represent a valuable tool and a promising target in the prevention, diagnosis and treatment of CAD in the clinical setting.}, author = {Vassalle, C. and Pratali, L. and Boni, C. and Mercuri, A. and Ndreu, R.}, citeulike-article-id = {3441140}, citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.clinbiochem.2008.07.005}, citeulike-linkout-1 = {http://linkinghub.elsevier.com/retrieve/pii/S0009912008002695}, doi = {10.1016/j.clinbiochem.2008.07.005}, issn = {00099120}, journal = {Clinical Biochemistry}, keywords = {antioxidant, artery, coronery, disease, oxidative, pro-oxidant, score, stress}, month = {October}, number = {14-15}, pages = {1162--1167}, posted-at = {2008-10-22 20:14:59}, priority = {2}, title = {An oxidative stress score as a combined measure of the pro-oxidant and anti-oxidant counterparts in patients with coronary artery disease}, url = {http://dx.doi.org/10.1016/j.clinbiochem.2008.07.005}, volume = {41}, year = {2008} }

TY - JOUR ID - citeulike:3441140 L3 - citeulike-article-id:3441140 N2 - Oxidative stress plays a key role in the pathogenesis and development of atherosclerosis. To evaluate the relationship between a novel oxidative stress index (reflecting both oxidative and anti-oxidant counterparts) with traditional cardiovascular risk factors and C-reactive protein (CRP) in coronary artery disease (CAD). 100 angiographically proven CAD and 70 control subjects (mean age: 65 ± 10 years, 110 males), underwent a global cardiovascular risk assessment and serum CRP and oxidative stress estimation. The Oxidative-INDEX was calculated after automated evaluation of serum hydroperoxides and total anti-oxidant capacity (D-ROM and OXY-adsorbent Test, Diacron, Italy) subtracting the OXY standardized variable from the ROM standardized variable. Oxidative stress represents a shared molecular pathway in atherosclerotic-related conditions, and its estimation by the automated Oxidative-INDEX could represent a valuable tool and a promising target in the prevention, diagnosis and treatment of CAD in the clinical setting. IS - 14-15 JF - Clinical Biochemistry SN - 00099120 EP - 1167 TI - An oxidative stress score as a combined measure of the pro-oxidant and anti-oxidant counterparts in patients with coronary artery disease VL - 41 SP - 1162 KW - antioxidant KW - artery KW - coronery KW - disease KW - oxidative KW - pro-oxidant KW - score KW - stress AU - Vassalle, C AU - Pratali, L AU - Boni, C AU - Mercuri, A AU - Ndreu, R PY - 2008/10// UR - http://dx.doi.org/10.1016/j.clinbiochem.2008.07.005 ER -