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Evolutionary origins of the obesity epidemic: natural selection of thrifty genes or genetic drift following predation release? |
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RIS record1 1918 2 20 20p11 3 3d4d a2 abbot abdominal acid activate activation active ada adaptive adipocyte adipogenesis adiponectin adipose admixture advances adverse aerobic african agent aids air alcohol algorithm alleles allergen alpha american americans anaerobic analysis ancestry and androgen ankle-brachial anti antibodies antibody antioxidant apo architech artery artificial assay assembly assistance assocation association atg7 atherogenic attack attractor authorization autoimmunity automata autonomic autophagy b bacteria bacteriotherapy baldness barcode bariatric base based bayesian behavior best beta binding bioinformatics biological biology biomarker biomedical biomimetic biosensors biotechnology bipartite blocker blood breakdown breast c calcium caliper cancer candidate candidates carbon cardiovascular case cases cbr ccr5 cd36 cd4 cd8 cdms cell cellml cells cellular centers challenges change channel cheap chemical chemistries chemistry chemotherapy china chip cholesterol chromosome chronic circadian circulating class classificatin classification classifier clinical clostridium clustering cobas cohort colon colorimetric commercial common comparative compare comparison compensatory comprehensive computation concept consent contracts contrast control core coronery cotranscription creative creativity critically criticism cyclic cytokine darapladib data database deacetylase decision delivery dendritic dependence design development diabetes diacylglycerol diagnosis diagnostics different differentially disambiguation discovery discrete disease disorder dna drift drifty drosha drug drugs duodenal dynamic dysfunction dyslipoproteinemia early ebf1 ecm ecosystem effect effects elementary elements emergent endogenous energy engineered engineering engineers enrichment enterpreneurship enthalpy entropy environment estimation ethnicity evalution events evidence evolution exonuclease expressed expression extracellular factor factorial failure family fasting fat fatty fda feature fibrosis field first force foxo1 framework free from fto function functional fusion future gain gastrointenstinal gene genes genetic genetics genminer gennid genome genomics genotype glucose glucotoxicity glycerol glycolysis glycoside glycosyltransferases gpr41 graph graphs gut hapmap hdl health healthcare heart helicos hepatitis high higher histone history hiv home homeostasis hosts human hydrolases hypermutation hypocaloric hypothesis hypoxic identy ill imaging immunity immunoassays immunology immunotherapy impact implementation in inactivation independent index india inductive infection inflammaiton inflammation influenza information infusion inhibitor innate insulin intake integrated integration intelligence intelligent interactions interferon interview intestine inverse isoleucine italy jazf1 knowledge lactic lactobacillus landscape language lasting lcat learning leptin leucine leukemia licensing life lineage linear link linkage lipids lipolysis lipoprotein-associated liver loci logistic long luciferase lymphoid macrophage made management mangabee mapping marker markers marketing mashup matrix medical medicine memory metabolic metabolism metastasis methyltransferase mice microarray microbes microbial microbiome microbiota microfluidics microliter microrna milestones misdirected mitochondria mitochondrial mixture mll3 mode model modeling models modification molecule mortality motifs motivation mouse mrna mucosal multiplex multitarget muscle mutated myeloperoxidase myocyte nanoparticle nanotechnology nanotube nanowire natural necrotic nervous network networks neuronal neutralizing new nih nitric no nonequilibrium nonfasting nongradient npy numeric nutrient obese obesity odds of o-glcnac oleoylethanolamide omega omics oncolytic onset ontology optimal options ordered osteoblast osteopontin outcome oxidation oxidative oxide oxygen pancreatic paper paradigm paradox parsimony particle pathway pediatric peptide performance peripheral personal personalized pgc1 pharma pharmacogenetics pharmacology phenotype phenotypes phospholipase photoacoustic pitfall pkc plasma plasmaykl40 pollution polymorphism polymorphisms population postfusion potential power precaution predation predict prediction predictive prevent probability probiotics procalcitonin processing production productivity profiles profiling program proof pro-oxidant prospects prostate protection protein proteolysis proteomic proteomics proteomicssmall proxy qsar r radiation radical radiosensitivity range rat ratios rats reasoning receptor reciprocal recoveryweight reduce reference references regression relation release rems reservoir resistance response retina reversal reverse review rhythm risk robust robustgene roc roche royalties rules safety satiety scientific score screening secreted selected selection semantic sense sensing sensitivity sepsis sequencing set signal signaling signals signature similarity simulation single siv size small snp social somatic sooty stability status steatohepatitis stochasticity strategic stratification strength stress structure studies subnetwork sugar support supramolecular surgery surrogate susceptibility synopses synthase synthesis synthetic system systems t tape targeted tcf2 tcf7l2 techniques technologies technology test text th2 therapeutic therapeutics thresholding thrifty timecourse tips tlr tolerant transcription transcriptome transcriptomic transgenic translating translational transport transthyretin trends trial trials triglyceride tumor type use vaccine vaccines validation variants variation vasculature ventricular viral viruses visfatin visualization warburg web weight wide women word zebrafish




