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Phase-sensitive swept-source optical coherence tomography imaging of the human retina with a vertical cavity surface-emitting laser light source

by: WooJhon Choi, Benjamin Potsaid, Vijaysekhar Jayaraman, Bernhard Baumann, Ireneusz Grulkowski, Jonathan J. Liu, Chen D. Lu, Alex E. Cable, David Huang, Jay S. Duker, James G. Fujimoto
Opt. Lett., Vol. 38, No. 3. (1 February 2013), pp. 338-340, doi:10.1364/ol.38.000338  Key: citeulike:11969791

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Abstract

Despite the challenges in achieving high phase stability, Doppler swept-source/Fourier-domain optical coherence tomography (OCT) has advantages of less fringe washout and faster imaging speeds compared to spectral/Fourier-domain detection. This Letter demonstrates swept-source OCT with a vertical cavity surface-emitting laser light source at 400 kHz sweep rate for phase-sensitive Doppler imaging, measuring pulsatile total retinal blood flow with high sensitivity and phase stability. A robust, simple, and computationally efficient phase stabilization approach for phase-sensitive swept-source imaging is also presented.


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