Antibody responses to Acinetobacter spp. and Pseudomonas aeruginosa in multiple sclerosis: prospects for diagnosis using the myelin-acinetobacter-neurofilament antibody index. Export

@article{citeulike:4051888, abstract = {Antibody responses to Acinetobacter (five strains), Pseudomonas aeruginosa, Escherichia coli, myelin basic protein (MBP), and neurofilaments were measured in sera from 26 multiple sclerosis (MS) patients, 20 patients with cerebrovascular accidents (CVA), 10 patients with viral encephalitis, and 25 healthy blood donors. In MS patients, elevated levels of antibodies against all strains of Acinetobacter tested were present, as well as antibodies against P. aeruginosa, MBP, and neurofilaments, but not antibodies to E. coli, compared to the CVA group and controls. The myelin-Acinetobacter-neurofilament antibody index appears to distinguish MS patients from patients with CVAs or healthy controls. The relevance of such antibodies to the neuropathology of MS requires further evaluation.}, author = {Hughes, L. E. and Bonell, S. and Natt, R. S. and Wilson, C. and Tiwana, H. and Ebringer, A. and Cunningham, P. and Chamoun, V. and Thompson, E. J. and Croker, J. and Vowles, J.}, citeulike-article-id = {4051888}, citeulike-linkout-0 = {http://dx.doi.org/10.1128/CDLI.8.6.1181-1188.2001}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/11687461}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=11687461}, doi = {10.1128/CDLI.8.6.1181-1188.2001}, issn = {1071-412X}, journal = {Clinical and diagnostic laboratory immunology}, keywords = {acinetobacter, autoimmune, immune\_system, infection, molecular\_mimicry, multiple\_sclerosis, myelin}, month = {November}, number = {6}, pages = {1181--1188}, posted-at = {2009-02-14 15:29:04}, priority = {2}, title = {Antibody responses to Acinetobacter spp. and Pseudomonas aeruginosa in multiple sclerosis: prospects for diagnosis using the myelin-acinetobacter-neurofilament antibody index.}, url = {http://dx.doi.org/10.1128/CDLI.8.6.1181-1188.2001}, volume = {8}, year = {2001} }

TY - JOUR ID - citeulike:4051888 L3 - citeulike-article-id:4051888 N2 - Antibody responses to Acinetobacter (five strains), Pseudomonas aeruginosa, Escherichia coli, myelin basic protein (MBP), and neurofilaments were measured in sera from 26 multiple sclerosis (MS) patients, 20 patients with cerebrovascular accidents (CVA), 10 patients with viral encephalitis, and 25 healthy blood donors. In MS patients, elevated levels of antibodies against all strains of Acinetobacter tested were present, as well as antibodies against P. aeruginosa, MBP, and neurofilaments, but not antibodies to E. coli, compared to the CVA group and controls. The myelin-Acinetobacter-neurofilament antibody index appears to distinguish MS patients from patients with CVAs or healthy controls. The relevance of such antibodies to the neuropathology of MS requires further evaluation. IS - 6 JF - Clinical and diagnostic laboratory immunology SN - 1071-412X EP - 1188 TI - Antibody responses to Acinetobacter spp. and Pseudomonas aeruginosa in multiple sclerosis: prospects for diagnosis using the myelin-acinetobacter-neurofilament antibody index. VL - 8 SP - 1181 KW - acinetobacter KW - autoimmune KW - immune_system KW - infection KW - molecular_mimicry KW - multiple_sclerosis KW - myelin AU - Hughes, LE AU - Bonell, S AU - Natt, RS AU - Wilson, C AU - Tiwana, H AU - Ebringer, A AU - Cunningham, P AU - Chamoun, V AU - Thompson, EJ AU - Croker, J AU - Vowles, J PY - 2001/11// UR - http://dx.doi.org/10.1128/CDLI.8.6.1181-1188.2001 ER -