How to interpret and pursue an abnormal prothrombin time, activated partial thromboplastin time, and bleeding time in adults. Export

@article{citeulike:1466299, abstract = {The prothrombin time (PT) and activated partial thromboplastin time (APTT) are among the most commonly ordered coagulation tests. In 2005, more than 140,000 PT and more than 95,000 APTT tests were performed at Mayo Clinic. The most common indications for ordering these tests include anticoagulant monitoring, initial evaluation of hemorrhage, and, although not generally indicated, routine preoperative screening. In addition, the bleeding time (BT) test, which is infrequently performed, is still available in certain institutions. Abnormal results from these tests (prolonged PT, APTT, and BT), especially from tests conducted for initial evaluation of hemorrhage or for preoperative screening, may pose a diagnostic dilemma to the nonhematologist. We review the essential factors affecting test results; provide a practical approach to the evaluation of a prolonged PT, APTT, and BT; and offer suggestions on which reflexive tests are appropriate and when to consider a subspecialty consultation.}, address = {Division of Hematology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (e-mail: pruthi.rajiv@mayo.edu).}, author = {Kamal, A. H. and Tefferi, A. and Pruthi, R. K.}, citeulike-article-id = {1466299}, citeulike-linkout-0 = {http://view.ncbi.nlm.nih.gov/pubmed/17605969}, citeulike-linkout-1 = {http://www.hubmed.org/display.cgi?uids=17605969}, issn = {0025-6196}, journal = {Mayo Clin Proc}, keywords = {anesthesia, bleeding, result, surgery, test, time}, month = {July}, number = {7}, pages = {864--873}, posted-at = {2008-05-19 15:08:50}, priority = {2}, title = {How to interpret and pursue an abnormal prothrombin time, activated partial thromboplastin time, and bleeding time in adults.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/17605969}, volume = {82}, year = {2007} }

TY - JOUR ID - citeulike:1466299 L3 - citeulike-article-id:1466299 N2 - The prothrombin time (PT) and activated partial thromboplastin time (APTT) are among the most commonly ordered coagulation tests. In 2005, more than 140,000 PT and more than 95,000 APTT tests were performed at Mayo Clinic. The most common indications for ordering these tests include anticoagulant monitoring, initial evaluation of hemorrhage, and, although not generally indicated, routine preoperative screening. In addition, the bleeding time (BT) test, which is infrequently performed, is still available in certain institutions. Abnormal results from these tests (prolonged PT, APTT, and BT), especially from tests conducted for initial evaluation of hemorrhage or for preoperative screening, may pose a diagnostic dilemma to the nonhematologist. We review the essential factors affecting test results; provide a practical approach to the evaluation of a prolonged PT, APTT, and BT; and offer suggestions on which reflexive tests are appropriate and when to consider a subspecialty consultation. IS - 7 JF - Mayo Clin Proc SN - 0025-6196 AD - Division of Hematology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (e-mail: pruthi.rajiv@mayo.edu). EP - 873 TI - How to interpret and pursue an abnormal prothrombin time, activated partial thromboplastin time, and bleeding time in adults. VL - 82 SP - 864 KW - anesthesia KW - bleeding KW - result KW - surgery KW - test KW - time AU - Kamal, AH AU - Tefferi, A AU - Pruthi, RK PY - 2007/07// UR - http://view.ncbi.nlm.nih.gov/pubmed/17605969 ER -