Molecular imaging in cancer. Export

@article{citeulike:1355526, abstract = {Medical imaging technologies have undergone explosive growth over the past few decades and now play a central role in clinical oncology. But the truly transformative power of imaging in the clinical management of cancer patients lies ahead. Today, imaging is at a crossroads, with molecularly targeted imaging agents expected to broadly expand the capabilities of conventional anatomical imaging methods. Molecular imaging will allow clinicians to not only see where a tumor is located in the body, but also to visualize the expression and activity of specific molecules (e.g., proteases and protein kinases) and biological processes (e.g., apoptosis, angiogenesis, and metastasis) that influence tumor behavior and/or response to therapy. This information is expected to have a major impact on cancer detection, individualized treatment, and drug development, as well as our understanding of how cancer arises.}, address = {Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA. weissleder@helix.mgh.harvard.edu}, author = {Weissleder, R.}, citeulike-article-id = {1355526}, citeulike-linkout-0 = {http://dx.doi.org/10.1126/science.1125949}, citeulike-linkout-1 = {http://www.sciencemag.org/cgi/content/abstract/312/5777/1168}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/16728630}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=16728630}, day = {26}, doi = {10.1126/science.1125949}, issn = {1095-9203}, journal = {Science}, keywords = {bio, bioimage, cancer, imaging, molecular}, month = {May}, number = {5777}, pages = {1168--1171}, posted-at = {2009-03-24 22:52:57}, priority = {2}, title = {Molecular imaging in cancer.}, url = {http://dx.doi.org/10.1126/science.1125949}, volume = {312}, year = {2006} }

TY - JOUR ID - citeulike:1355526 L3 - citeulike-article-id:1355526 N2 - Medical imaging technologies have undergone explosive growth over the past few decades and now play a central role in clinical oncology. But the truly transformative power of imaging in the clinical management of cancer patients lies ahead. Today, imaging is at a crossroads, with molecularly targeted imaging agents expected to broadly expand the capabilities of conventional anatomical imaging methods. Molecular imaging will allow clinicians to not only see where a tumor is located in the body, but also to visualize the expression and activity of specific molecules (e.g., proteases and protein kinases) and biological processes (e.g., apoptosis, angiogenesis, and metastasis) that influence tumor behavior and/or response to therapy. This information is expected to have a major impact on cancer detection, individualized treatment, and drug development, as well as our understanding of how cancer arises. IS - 5777 JF - Science SN - 1095-9203 AD - Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA. weissleder@helix.mgh.harvard.edu EP - 1171 TI - Molecular imaging in cancer. VL - 312 SP - 1168 KW - bio KW - bioimage KW - cancer KW - imaging KW - molecular AU - Weissleder, R PY - 2006/05/26/ UR - http://dx.doi.org/10.1126/science.1125949 ER -