A shape analysis framework for small animal phenotyping with application to mice with a targeted disruption of Hoxd11 Export

@inproceedings{citeulike:6051795, abstract = {This paper proposes the use of high-dimensional, point-based shape models for the study of phenotype, which offer some important advantages over traditional morphometries, including a more detailed representation of shape and a more systematic approach to shape statistics. Our approach allows for the analysis of shape at both global and local scales and can automatically extract lower- dimensional shape features useful for phenotypic characterization. We also demonstrate how covariates can be included in this framework. We apply the proposed modeling framework to a study of bone shape in mice with a targeted disruption of the Hoxd11 gene.}, author = {Cates, J. and Fletcher, P. T. and Warnock, Z. and Whitaker, R.}, citeulike-article-id = {6051795}, citeulike-linkout-0 = {http://dx.doi.org/10.1109/ISBI.2008.4541045}, citeulike-linkout-1 = {http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=4541045}, day = {13}, doi = {10.1109/ISBI.2008.4541045}, journal = {Biomedical Imaging: From Nano to Macro, 2008. ISBI 2008. 5th IEEE International Symposium on}, keywords = {pdm, shape\_analysis}, month = {June}, pages = {512--515}, posted-at = {2009-10-31 21:46:22}, priority = {2}, title = {A shape analysis framework for small animal phenotyping with application to mice with a targeted disruption of Hoxd11}, url = {http://dx.doi.org/10.1109/ISBI.2008.4541045}, year = {2008} }

TY - CONF ID - citeulike:6051795 L3 - citeulike-article-id:6051795 N2 - This paper proposes the use of high-dimensional, point-based shape models for the study of phenotype, which offer some important advantages over traditional morphometries, including a more detailed representation of shape and a more systematic approach to shape statistics. Our approach allows for the analysis of shape at both global and local scales and can automatically extract lower- dimensional shape features useful for phenotypic characterization. We also demonstrate how covariates can be included in this framework. We apply the proposed modeling framework to a study of bone shape in mice with a targeted disruption of the Hoxd11 gene. JF - Biomedical Imaging: From Nano to Macro, 2008. ISBI 2008. 5th IEEE International Symposium on EP - 515 TI - A shape analysis framework for small animal phenotyping with application to mice with a targeted disruption of Hoxd11 SP - 512 KW - pdm KW - shape_analysis AU - Cates, J AU - Fletcher, PT AU - Warnock, Z AU - Whitaker, R PY - 2008/06/13/ UR - http://dx.doi.org/10.1109/ISBI.2008.4541045 ER -