Cerebellar cortical degeneration with selective granule cell loss in Bavarian mountain dogs Export

@article{citeulike:1512201, abstract = {Three Bavarian mountain dogs aged between 18 and 20 months, not related to each other, were presented with chronic signs of cerebellar dysfunction. On sagittal T2-weighted magnetic resonance imaging brain images, the tentative diagnosis of cerebellar hypoplasia was established based on an enlarged cerebrospinal fluid space around the cerebellum and an increased cerebrospinal fluid signal between the folia. Post-mortem examination was performed in one dog and did show an overall reduction of cerebellar size. On histopathologic examination, a selective loss of cerebellar granule cells with sparing of Purkinje cells was evident. Therefore, the Bavarian mountain dog is a breed where cerebellar cortical degeneration caused by the rather exceptional selective granule cell loss can be seen as cause of chronic, slowly progressive cerebellar dysfunction starting at an age of several months.}, author = {Flegel, T. and Matiasek, K. and Henke, D. and Grevel, V.}, citeulike-article-id = {1512201}, citeulike-linkout-0 = {http://www.blackwell-synergy.com/doi/abs/10.1111/j.1748-5827.2006.00257.x}, citeulike-linkout-1 = {http://dx.doi.org/10.1111/j.1748-5827.2006.00257.x}, citeulike-linkout-2 = {http://view.ncbi.nlm.nih.gov/pubmed/17663663}, citeulike-linkout-3 = {http://www.hubmed.org/display.cgi?uids=17663663}, doi = {10.1111/j.1748-5827.2006.00257.x}, journal = {Journal of Small Animal Practice}, keywords = {bavarian-mountain-dog, cerebellum, cortex, degeneration, dog}, number = {8}, pages = {462--465}, posted-at = {2007-08-17 17:52:58}, priority = {2}, title = {Cerebellar cortical degeneration with selective granule cell loss in Bavarian mountain dogs}, url = {http://dx.doi.org/10.1111/j.1748-5827.2006.00257.x}, volume = {48}, year = {2007} }

TY - JOUR ID - citeulike:1512201 L3 - citeulike-article-id:1512201 N2 - Three Bavarian mountain dogs aged between 18 and 20 months, not related to each other, were presented with chronic signs of cerebellar dysfunction. On sagittal T2-weighted magnetic resonance imaging brain images, the tentative diagnosis of cerebellar hypoplasia was established based on an enlarged cerebrospinal fluid space around the cerebellum and an increased cerebrospinal fluid signal between the folia. Post-mortem examination was performed in one dog and did show an overall reduction of cerebellar size. On histopathologic examination, a selective loss of cerebellar granule cells with sparing of Purkinje cells was evident. Therefore, the Bavarian mountain dog is a breed where cerebellar cortical degeneration caused by the rather exceptional selective granule cell loss can be seen as cause of chronic, slowly progressive cerebellar dysfunction starting at an age of several months. IS - 8 JF - Journal of Small Animal Practice EP - 465 TI - Cerebellar cortical degeneration with selective granule cell loss in Bavarian mountain dogs VL - 48 SP - 462 KW - bavarian-mountain-dog KW - cerebellum KW - cortex KW - degeneration KW - dog AU - Flegel, T AU - Matiasek, K AU - Henke, D AU - Grevel, V PY - 2007/// UR - http://dx.doi.org/10.1111/j.1748-5827.2006.00257.x ER -