Macronuclear Genome Sequence of the Ciliate <italic>Tetrahymena thermophila,</italic> a Model Eukaryote Export

@article{citeulike:4695121, abstract = {<p>The macronuclear genome of<italic>Tetrahymena thermophila</italic> is sequenced and analyzed. Conservation in this single-celled ciliate of some features normally observed in only multicellular organisms sheds light on early eukaryotic evolution.</p>}, author = {Eisen, Jonathan A. and Coyne, Robert S. and Wu, Martin and Wu, Dongying and Thiagarajan, Mathangi and Wortman, Jennifer R. and Badger, Jonathan H. and Ren, Qinghu and Amedeo, Paolo and Jones, Kristie M. and Tallon, Luke J. and Delcher, Arthur L. and Salzberg, Steven L. and Silva, Joana C. and Haas, Brian J. and Majoros, William H. and Farzad, Maryam and Carlton, Jane M. and Smith, Roger K. and Garg, Jyoti and Pearlman, Ronald E. and Karrer, Kathleen M. and Sun, Lei and Manning, Gerard and Elde, Nels C. and Turkewitz, Aaron P. and Asai, David J. and Wilkes, David E. and Wang, Yufeng and Cai, Hong and Collins, Kathleen and Stewart, Andrew B. and Lee, Suzanne R. and Wilamowska, Katarzyna and Weinberg, Zasha and Ruzzo, Walter L. and Wloga, Dorota and Gaertig, Jacek and Frankel, Joseph and Tsao, Che-Chia and Gorovsky, Martin A. and Keeling, Patrick J. and Waller, Ross F. and Patron, Nicola J. and Cherry, Michael J. and Stover, Nicholas A. and Krieger, Cynthia J. and Del and Ryder, Hilary F. and Williamson, Sondra C. and Barbeau, Rebecca A. and Hamilton, Eileen P. and Orias, Eduardo}, citeulike-article-id = {4695121}, citeulike-linkout-0 = {http://dx.doi.org/10.1371/journal.pbio.0040286}, comment = {Found via a search in PLoS Biology for "kinesin." I only read the abstract but learned that Tetrahymena has two nuclei--one for sexual reproduction (MIC) and one for gene expression (MAC). This is fascinating to me, and hopefully someday I can learn about it. At this point, I have no idea what benefits this could have for the organism. I also wonder how it impacts DNA damage repair and genome stability. }, doi = {10.1371/journal.pbio.0040286}, journal = {PLoS Biol}, keywords = {cool, tetrahymena}, month = {August}, number = {9}, pages = {e286+}, posted-at = {2009-06-01 00:16:04}, priority = {2}, publisher = {Public Library of Science}, title = {Macronuclear Genome Sequence of the Ciliate <italic>Tetrahymena thermophila,</italic> a Model Eukaryote}, url = {http://dx.doi.org/10.1371/journal.pbio.0040286}, volume = {4}, year = {2006} }

TY - JOUR ID - citeulike:4695121 L3 - citeulike-article-id:4695121 N2 - <p>The macronuclear genome of<italic>Tetrahymena thermophila</italic> is sequenced and analyzed. Conservation in this single-celled ciliate of some features normally observed in only multicellular organisms sheds light on early eukaryotic evolution.</p> IS - 9 JF - PLoS Biol TI - Macronuclear Genome Sequence of the Ciliate <italic>Tetrahymena thermophila,</italic> a Model Eukaryote PB - Public Library of Science VL - 4 SP - e286 KW - cool KW - tetrahymena N1 - Found via a search in PLoS Biology for "kinesin." I only read the abstract but learned that Tetrahymena has two nuclei--one for sexual reproduction (MIC) and one for gene expression (MAC). This is fascinating to me, and hopefully someday I can learn about it. At this point, I have no idea what benefits this could have for the organism. I also wonder how it impacts DNA damage repair and genome stability. AU - Eisen, Jonathan AU - Coyne, Robert AU - Wu, Martin AU - Wu, Dongying AU - Thiagarajan, Mathangi AU - Wortman, Jennifer AU - Badger, Jonathan AU - Ren, Qinghu AU - Amedeo, Paolo AU - Jones, Kristie AU - Tallon, Luke AU - Delcher, Arthur AU - Salzberg, Steven AU - Silva, Joana AU - Haas, Brian AU - Majoros, William AU - Farzad, Maryam AU - Carlton, Jane AU - Smith, Roger AU - Garg, Jyoti AU - Pearlman, Ronald AU - Karrer, Kathleen AU - Sun, Lei AU - Manning, Gerard AU - Elde, Nels AU - Turkewitz, Aaron AU - Asai, David AU - Wilkes, David AU - Wang, Yufeng AU - Cai, Hong AU - Collins, Kathleen AU - Stewart, Andrew AU - Lee, Suzanne AU - Wilamowska, Katarzyna AU - Weinberg, Zasha AU - Ruzzo, Walter AU - Wloga, Dorota AU - Gaertig, Jacek AU - Frankel, Joseph AU - Tsao, Che-Chia AU - Gorovsky, Martin AU - Keeling, Patrick AU - Waller, Ross AU - Patron, Nicola AU - Cherry, Michael AU - Stover, Nicholas AU - Krieger, Cynthia AU - Del AU - Ryder, Hilary AU - Williamson, Sondra AU - Barbeau, Rebecca AU - Hamilton, Eileen AU - Orias, Eduardo PY - 2006/08/29/ UR - http://dx.doi.org/10.1371/journal.pbio.0040286 ER -