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Circulation, Vol. 94, No. 12. (15 December 1996), pp. 3334-3340, doi:10.1161/01.cir.94.12.3334 Key: citeulike:6375372
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Background In this work, we report a novel targetable ultrasonic contrast agent with the potential to noninvasively define and localize myriad pathological tissues for diagnosis or therapy. The agent is a biotinylated, lipid-coated, perfluorocarbon emulsion that has low inherent echogenicity unless bound to a surface or itself.
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