Free Brownian Motion of Individual Lipid Molecules in Biomembranes Export

@article{citeulike:2316902, abstract = {The mobility of phospolipids in free-standing and supported membranes was investigated on the level of individual molecules. For the analysis of trajectories a new statistical treatment was developed that permitted us to clearly distinguish different types of diffusional motion. A freely diffusing subfraction of lipids within supported membranes was identified. Its mobility was characterized by a mean lateral diffusion constant of Dsupp = 4.6 {micro}m2/s. In comparison, the mobility of lipids embedded in "free-standing" planar membranes yielded an increase in the mean diffusion constant by a factor of 4.5, Dfree = 20.6 {micro}m2/s. This increase is attributed to the ultrathin ([\<=]1 nm) lubricating water layer between membranes and glass support.}, author = {Sonnleitner, A. and Schutz, G. J. and Schmidt, Th}, citeulike-article-id = {2316902}, citeulike-linkout-0 = {http://www.biophysj.org/cgi/content/abstract/77/5/2638}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/10545363}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=10545363}, day = {1}, journal = {Biophys. J.}, keywords = {brownian-motion, diffusion}, month = {November}, number = {5}, pages = {2638--2642}, posted-at = {2008-01-31 23:59:20}, priority = {2}, title = {Free Brownian Motion of Individual Lipid Molecules in Biomembranes}, url = {http://www.biophysj.org/cgi/content/abstract/77/5/2638}, volume = {77}, year = {1999} }

TY - JOUR ID - citeulike:2316902 L3 - citeulike-article-id:2316902 N2 - The mobility of phospolipids in free-standing and supported membranes was investigated on the level of individual molecules. For the analysis of trajectories a new statistical treatment was developed that permitted us to clearly distinguish different types of diffusional motion. A freely diffusing subfraction of lipids within supported membranes was identified. Its mobility was characterized by a mean lateral diffusion constant of Dsupp = 4.6 {micro}m2/s. In comparison, the mobility of lipids embedded in "free-standing" planar membranes yielded an increase in the mean diffusion constant by a factor of 4.5, Dfree = 20.6 {micro}m2/s. This increase is attributed to the ultrathin ([<=]1 nm) lubricating water layer between membranes and glass support. IS - 5 JF - Biophys. J. EP - 2642 TI - Free Brownian Motion of Individual Lipid Molecules in Biomembranes VL - 77 SP - 2638 KW - brownian-motion KW - diffusion AU - Sonnleitner, A AU - Schutz, GJ AU - Schmidt, Th PY - 1999/11/01/ UR - http://www.biophysj.org/cgi/content/abstract/77/5/2638 ER -