Social network and coronary artery calcification in asymptomatic individuals. Export

@article{citeulike:6098096, abstract = {BACKGROUND: Psychosocial factors are associated with the development of coronary artery disease. However, studies examining psychosocial factors as risk indicators for coronary artery calcification (CAC) have been inconclusive. METHODS: Seven hundred eighty-three participants (mean age 57.4 +/- 9.3 years, 47\% female) underwent CAC imaging using electron beam tomography. Psychosocial measures included social network (number of people in the household, marital status), socioeconomic status (education, income, and work status), history of depression, and current depressive symptoms as assessed with the Center for Epidemiologic Studies Depression (CES-D) scale. Assessments were also made for lipid profile, blood glucose, blood pressure, and health behaviors (smoking status, exercise, and diet). RESULTS: Calcification was present in 351 (44.8\%) participants (CAC score range 0-3022; mean 111.5 +/- 307.2). Indicators of social isolation (being single or widowed) were independently associated with elevated risk for the presence of CAC, even after adjustment for age, sex, systolic blood pressure, blood glucose, and low-density lipoprotein (adjusted odds ratios 1.80, 95\% confidence interval [CI] = 1.05-3.10, and 2.48, 95\% CI = 1.02-6.03, respectively). By contrast, health behaviors, socioeconomic status, and depressive symptoms were not related to CAC. CONCLUSIONS: Social network indices such as being single or widowed are associated with CAC, independent of age and coronary risk factors. Because coronary calcification has been identified as a potential marker of early atherosclerosis, these findings may partially explain the predictive value of limited social networks for future adverse cardiovascular health outcomes.}, author = {Kop, Willem J. and Berman, Daniel S. and Gransar, Heidi and Wong, Nathan D. and Miranda-Peats, Romalisa and White, Maria D. and Shin, Magnolia and Bruce, Melissa and Krantz, David S. and Rozanski, Alan}, citeulike-article-id = {6098096}, citeulike-linkout-0 = {http://dx.doi.org/10.1097/01.psy.0000161201.45643.8d}, citeulike-linkout-1 = {http://view.ncbi.nlm.nih.gov/pubmed/15911895}, citeulike-linkout-2 = {http://www.hubmed.org/display.cgi?uids=15911895}, doi = {10.1097/01.psy.0000161201.45643.8d}, issn = {1534-7796}, journal = {Psychosomatic medicine}, keywords = {calcification, chd, markers, network, social}, number = {3}, pages = {343--352}, posted-at = {2009-11-11 13:49:17}, priority = {2}, title = {Social network and coronary artery calcification in asymptomatic individuals.}, url = {http://dx.doi.org/10.1097/01.psy.0000161201.45643.8d}, volume = {67}, year = {2005} }

TY - JOUR ID - citeulike:6098096 L3 - citeulike-article-id:6098096 N2 - BACKGROUND: Psychosocial factors are associated with the development of coronary artery disease. However, studies examining psychosocial factors as risk indicators for coronary artery calcification (CAC) have been inconclusive. METHODS: Seven hundred eighty-three participants (mean age 57.4 +/- 9.3 years, 47% female) underwent CAC imaging using electron beam tomography. Psychosocial measures included social network (number of people in the household, marital status), socioeconomic status (education, income, and work status), history of depression, and current depressive symptoms as assessed with the Center for Epidemiologic Studies Depression (CES-D) scale. Assessments were also made for lipid profile, blood glucose, blood pressure, and health behaviors (smoking status, exercise, and diet). RESULTS: Calcification was present in 351 (44.8%) participants (CAC score range 0-3022; mean 111.5 +/- 307.2). Indicators of social isolation (being single or widowed) were independently associated with elevated risk for the presence of CAC, even after adjustment for age, sex, systolic blood pressure, blood glucose, and low-density lipoprotein (adjusted odds ratios 1.80, 95% confidence interval [CI] = 1.05-3.10, and 2.48, 95% CI = 1.02-6.03, respectively). By contrast, health behaviors, socioeconomic status, and depressive symptoms were not related to CAC. CONCLUSIONS: Social network indices such as being single or widowed are associated with CAC, independent of age and coronary risk factors. Because coronary calcification has been identified as a potential marker of early atherosclerosis, these findings may partially explain the predictive value of limited social networks for future adverse cardiovascular health outcomes. IS - 3 JF - Psychosomatic medicine SN - 1534-7796 EP - 352 TI - Social network and coronary artery calcification in asymptomatic individuals. VL - 67 SP - 343 KW - calcification KW - chd KW - markers KW - network KW - social AU - Kop, Willem AU - Berman, Daniel AU - Gransar, Heidi AU - Wong, Nathan AU - Miranda-Peats, Romalisa AU - White, Maria AU - Shin, Magnolia AU - Bruce, Melissa AU - Krantz, David AU - Rozanski, Alan PY - 2005///n UR - http://dx.doi.org/10.1097/01.psy.0000161201.45643.8d ER -